Although the HIV pandemic is witnessing a decline in the number of new infections in most regions of the world, the Middle East and North Africa (MENA) has a rapidly growing HIV problem. While generating HIV data has been consistently increasing since 2005, MENA’s contribution to the global HIV literature is just over 1% and the existing evidence often falls behind the academic standards. Sever...

In mammalian cells, the Golgi reassembly stacking protein 65 (GRASP65) has been implicated in both Golgi stacking and ribbon linking by forming trans-oligomers through the N-terminal GRASP domain. Because the GRASP domain is globular and relatively small, but the gaps between stacks are large and heterogeneous, it remains puzzling how GRASP65 physically links Golgi stacks into a ribbon. To expl...

PURPOSE OF REVIEW A volume of quality HIV data has materialized recently in the Middle East and North Africa (MENA). This review provides a thematic narrative of the patterns of HIV infection transmission in this region in light of these data. RECENT FINDINGS Tens of integrated bio-behavioral surveillance surveys among hard-to-reach key populations at higher risk have been conducted in MENA i...

the main objective of this paper is to analysis the impact of information and communication technology (ict) on energy consumption in the mena region selected countries during the period 1995-2011. for this purpose, used the model presented by sadorsky (2012) and three indicators that measured ict: the number of internet users, the number of mobile lines and the number of telephone lines. also,...

The aim of this paper is to investigate whether oil revenues in the MENA region lead economic growth or resource curse evident. To do so we employ a panel Vector Auto-Regressive (PVAR) model comprising not only and but also government expenditures. latter variable considered as examine revenue leads via fiscal policy channel. We further assess heterogeneous findings exist depending on quality p...

Mena [mammalian Ena (Enabled)]/VASP (vasodilator-stimulated phosphoprotein) proteins are the homologues of Drosophila Ena. In Drosophila, Ena is a substrate of the tyrosine kinase DAbl (Drosophila Abl). However, the link between Abl and the Mena/VASP family is not fully understood in mammals. We previously reported that Abi-1 (Abl interactor 1) promotes phosphorylation of Mena and BCAP (B-cell ...

BACKGROUND The Rho GTPases Rho, Rac, and Cdc42 regulate the organization of the actin cytoskeleton by interacting with multiple, distinct downstream effector proteins. Cdc42 controls the formation of actin bundle-containing filopodia at the cellular periphery. The molecular mechanism for this remains as yet unclear. RESULTS We report here that Cdc42 interacts with IRSp53/BAP2 alpha, an SH3 do...