Spliceosomal intron numbers and boundary sequences vary dramatically in eukaryotes. We found a striking correspondence between low intron number and strong sequence conservation of 5' splice sites (5'ss) across eukaryotic genomes. The phylogenetic pattern suggests that ancestral 5'ss were relatively weakly conserved, but that some lineages independently underwent both major intron loss and 5'ss...

The automotive marketplace has seen a steady increase in customer demands for quiet and more comfortable vehicles. A customer’s expectations for NVH refinement often contradicts the constraints for lightweight vehicle designs and the need for a powertrain with increased fuel efficiency. The driveline of a vehicle can be a substantial cause of NVH issues. Variants in the driveline architecture (...

Laser-plasma technology promises a drastic reduction of the size of high-energy electron accelerators. It could make free-electron lasers available to a broad scientific community and push further the limits of electron accelerators for high-energy physics. Furthermore, the unique femtosecond nature of the source makes it a promising tool for the study of ultrafast phenomena. However, applicati...

The effect of 10 and 25 kGy ?-irradiation on penicillin G plus procaine and sodium ampicillin has been assessed by different chemical and microbiological analytical methods. According to the chemical results obtained, the antibiotics showed a slight reduction in doses applied but the microbiological assays revealed that the activity of irradiated antibiotics did not reduce. Microbiological stud...

It is the responsibility of the pharmaceutical industry that these microbiological standards are maintained until secondary packaging of the drug product. Knowledge of the microbiological quality of the used excipients and active ingredients, microbiological monitoring of the environment in which the pharmaceuticals are produced, as well as release-testing of the final drug product contribute t...

Purpose: This retrospective study analyzes the adequacy of the empirical antimicrobial treatment for sepsis at the emergency department according to the results of the microbiological isolations and describes the associations between microbiological variables and mortality. Values for several clinical and microbiological variables were prospectively collected for a total of 101 patients. Cases ...

background : collection and storage of roof rain water have been practiced for long time ago in iran and many other countries. water of cisterns is usually used as potable water. in golestan province many of rural torkman residents reservoir the most part of their potable water from roof rain in cisterns. in this province there are over 2600 cisterns. methods : to study the water quality, micro...

Acute community-acquired bacterial meningitis (BM) requires rapid diagnosis so that suitable treatment can be instituted within 60 minutes of admitting the patient. The cornerstone of diagnostic examination is lumbar puncture, which enables microbiological analysis and determination of the cerebrospinal fluid (CSF) cytochemical characteristics. However, microbiological testing is not sufficient...

Background and Objectives: Increased environmental concerns about synthetic packaging have promoted developments of novel, environmentally-friendly edible films. In the present study, the quality parameters of chicken egg coated with pectin or pectin incorporated cinnamon hydrosol was assessed. Materials and Methods: Egg chicken were coated with pectin and pectin prepared with cinnamon hydroso...

  The effect of gamma radiation (1, 3 and 5 kGy) on microbial quality of farmed rainbow trout (Oncorhynchus mykiss) fillets which were stored under frozen conditions (-20° C) was studied by measuring microbiological changes in 5 months. Gamma irradiation and increasing of frozen storage time had significant effects (P < /i>