To investigate the effect of long non coding RNA MAGI2-antisense 3 on proliferation, invasion and migration cervical cancer cells underlying mechanism. SiHa were divided into plasmid cloning DNA group, DNA-MAGI2-antisense anti-microRNA-negative control anti-microRNA-31-5p 3+microRNAnegative group 3+microRNA-31-5p group; quantitative reverse transcription polymerase chain reaction was used to de...

Total flavones of Selaginella uncinata (Desv.) spring has inhibitory effects on cancer progression. The study aims to analyze the total breast cell tumor properties and possible mechanism. MDA-MB-231 cells were treated with or transfected anti-microRNA-negative control anti-microRNA-1269. In addition, microRNA-negative microRNA-1269 mimics-transfected exposed uncinata. Cell proliferation apopto...

cardiovascular disease has become the main factor of death and birth defects in the world. there are some therapeutic structures and drugs for curative and palliative therapy of the disease, but to the aim of accessing reliable therapy or to postpone onset of disease, especially for individuals with heritable coronary artery disease in their pedigree genetic engineering technologies are making ...

To investigate the effect of pristimerin on gefitinib resistance in lung cancer cells and its regulation microRNA-936. Lung cell HCC827 was cultured vitro, resistant HCC827/gefitinib established were randomly assigned to control group, pristimerin-L pristimerin-M pristimerin-H gefitinib+pristimerin gefitinib+microRNA-negative gefitinib+microRNA-936 gefitinib+pristimerin+anti-microRNA negative g...

To investigate the effect and molecular mechanism of vitexicarpin on biological behavior colorectal cancer cells is objective study. The human epithelial cell line Caco-2 were divided into control group, low, middle high dose groups vitexicarpin, plasmid cloning DNA-circ_0000419 DNA anti-microRNA-224 anti-microRNA-224-negative vitexicarpin+small interfering-circ_0000419 group vitexicarpin+micro...

Objective(s): The aim of the present study was to investigate the effects of genistein and exercise on the spatial memory and expression of microRNA-132, BDNF, and IGF-1 in the hippocampus of ovariectomized rats. Materials and Methods: Sixty animals were divided into six groups of control, sham, ovariectomy (OVX), ovariectomized with 8 weeks of genistein administration (OVX.G), with 8 weeks of ...