نتایج جستجو برای: mobility group box 1

تعداد نتایج: 3554463  

Journal: :iranian biomedical journal 0
leila sadat-hatamnezhad asghar tanomand javad mahmoudi siamak sandoghchian shotorbani

background: stroke is a leading cause of death all around the world, and ischemic stroke is considered to be the most common stroke type. toll-like receptors (tlrs) are important molecules for detection of both pathogen invasion and tissue damage. in this regard, the purpose of this study was to assess the expression level of tlr2 on monocytes in patients with ischemic stroke and to evaluate th...

Journal: :Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2010

Journal: :iranian journal of allergy, asthma and immunology 0
aleksandr zherebiatiev department of microbiology, virology, and immunology, zaporozhye state medical university, zaporozhye, ukraine aleksandr kamyshnyi department of microbiology, virology and immunology, zaporozhye state medical university, zaporozhye, ukraine

il-1β and il-17a are two cytokines with strong proinflammatory activities and are now known to be involved in a number of chronic inflammatory disorders. high-mobility group box 1 (hmgb1) is a nuclear protein regulating the expression of these proinflammatory cytokines. the nlrp3 inflammasome promotes the maturation of the il-1β and its activation has been shown as a critical mechanism in the p...

Journal: :Experimental and Therapeutic Medicine 2017

The pathogenesis of autism spectrum disorder (ASD) likely involves genetic and environmental factors, impacting the complex neurodevelopmental and behavioral abnormalities of the disorder. Scientific researches emerging within the past two decades suggest that immune dysfunction and inflammation have pathogenic influences through different mechanisms, all leading to both a chronic state of low ...

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