نتایج جستجو برای: mrna
تعداد نتایج: 152959 فیلتر نتایج به سال:
Estrous cycle is one of the placental mammal characteristics after sexual maturity, including estrus stage (ES) and diestrus (DS). important in female physiology its disorder may lead to diseases, such as polycystic ovary syndrome, ovarian carcinoma, anxiety, epilepsy. In latest years, effects non-coding RNAs messenger RNA (mRNA) on estrous have started arouse much concern, however, a whole tra...
هدف از پژوهش حاضر، بررسی تأثیر شدت تمرین ورزشی بر ظرفیت نوزایی قلبی در رتهای مبتلا به آنفارکتوس میوکارد (MI) بود. به این منظور، ابتدا رتهای نر نژاد ویستار تحت عمل جراحی بستن شریان کرونری LAD قرار گرفتند و سپس از طریق اکوکاردیوگرافی ایجاد MI تأیید شد. چهار هفته پس از جراحی، رتهای مبتلا به MI بهصورت تصادفی در گروههای تمرین ورزشی با شدتهای کم (LIT)، متوسط (MIT)، بالا (HIT) و شم (Sham) به اضا...
Introduction: In order to study the alterations of beta 1 and 2 integrins mRNA level in rat lumbar spinal cord following the induction of chronic pain and its effect on the development of tolerance to morphine analgesia, we examined the level of expression of these genes in the presence of chronic pain, which is an inhibitor of morphine tolerance. We used induction of chronic pain alone and ...
Introduction: The effect of regular exercise in decreasing the incidence of heart diseases is well known. The abuse of anabolic androgenic steroids (AAS) has been associated with cardiovascular disorders. Uncoupling proteins (UCPs) transport protons across the inner mitochondrial membrane thereby proton gradient can be diminished by the action of UCPs. This process will result in the uncoupl...
Background: Currently, ARTs are of indispensable importance in treatment of human infertility. While ARTs are considered to be safe, some studies suggest that ARTs manipulations may perturb the epigenetic information and subsequently the health of the offspring. To examine these events further, this study was conducted to assess the effect of superovulation, in vitro culture and vitrification o...
مقدمه و هدف: فرض شده است که نوروتروفین-4/5 و گیرنده تیروزینکیناز B در سازگاری هماهنگ دستگاه عصبی عضلانی به افزایش فعالیت درگیر هستند. هدف از تحقیق حاضر بررسی تاثیر یک جلسه تمرین مقاومتی بر بیان mRNA نوروتروفین-4/5 و گیرنده تیروزین کیناز B در عضلات کند و تند انقباض موشهای صحرایی بود. روششناسی: در این تحقیق، تعداد 16 سر موش نر ویستار به طور تصادفی در دو گروه 8 تایی [تمرین مقاومتی ( T ) و ک...
A new diagnostic tool for the identification of differential item functioning (DIF) is proposed. Classical approaches to DIF allow to consider only few subpopulations like ethnic groups when investigating if the solution of items depends on the membership to a subpopulation. We propose an explicit model for differential item functioning that includes a set of variables, containing metric as wel...
The CCR4-NOT complex is a highly conserved, multifunctional machinery with a general role in controlling mRNA metabolism. It has been implicated in a number of different aspects of mRNA and protein expression, including mRNA degradation, transcription initiation and elongation, ubiquitination, and protein modification. The core CCR4-NOT complex is evolutionarily conserved and consists of at lea...
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