Past studies have suggested attentional control tasks such as the Stroop task and the task-switching paradigm may be sensitive for the early detection of dementia of the Alzheimer's type (DAT). The authors of the current study combined these tasks to create a Stroop switching task. Performance was compared across young adults, older adults, and individuals diagnosed with very mild dementia. Res...

Native cellular fluorescence (NCF) represents the innate capacity of tissues to absorb and emit light of specified wavelengths. Recent advances in optical engineering and computer technology have provided the, opportunity to measure NCF characteristics of various tissues in vivo. This report will briefly review the current status of NCF analysis of various neoplastic tissues. The status of inve...

We sought to test the hypothesis that mutant bacterial strains could be discriminated from each other on the basis of the metabolites they secrete into the medium (their 'metabolic footprint'), using two methods of 'global' metabolite analysis (FT-IR and direct injection electrospray mass spectrometry). The biological system used was based on a published study of Escherichia coli tryptophan mut...

BACKGROUND The NeuroTrax Mindstreams computerized cognitive assessment system was designed for widespread clinical and research use in detecting mild cognitive impairment (MCI). However, the capability of Mindstreams tests to discriminate elderly with MCI from those who are cognitively healthy has yet to be evaluated. Moreover, the comparability between these tests and traditional neuropsycholo...

To achieve a certain sensory outcome, multiple actions can be executed. For example, unlocking a door might require clockwise or counterclockwise key turns depending on regional norms. Using fMRI in healthy human subjects, we examined the neural networks that dissociate intended sensory outcome from underlying motor actions. Subjects controlled a figure on a computer screen by performing pen tr...

A fast trigger system is being designed as a potential upgrade to VERITAS, or as the basis for a future array of imaging atmospheric-Cherenkov telescopes such as AGIS. The scientific goal is a reduction of the energy threshold1by a factor of 2 over the current threshold of VERITAS of around 130 GeV. The trigger is being designed to suppress both accidentals from the night-sky background and cos...

The intrinsic idea of superdense coding is to find as many gates as possible such that they can be perfectly discriminated. In this paper, we consider a new scheme of discrimination of quantum gates, called ancillaassisted discrimination, in which a set of quantum gates on a d−dimensional system are perfectly discriminated with assistance from an r−dimensional ancilla system. The main contribut...

The role of the hippocampus in spatial learning and memory has been extensively studied in rodents. Comparable studies in nonhuman primates, however, are few, and findings are often contradictory. This may be attributable to the failure to distinguish between allocentric and egocentric spatial representations in experimental designs. For this experiment, six adult monkeys received bilateral hip...