نتایج جستجو برای: p l a x i s
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the aim of this study was to design orally disintegrating tablets of olanzapine and to complex olanzapine with 2-hydroxypropyl-β- cyclodextrin with special emphasis on disintegration and dissolution studies. phase solubility studies demonstrated the formation of 1:1 molar inclusion complex by kneading method. tablets were prepared by using superdisintegrants namely, sodium starch glycolate, cro...
alnus glutinosa, fraxinus excelsior and papaver rhoeas have long been used in folkloric medicine for the treatment of various ailments. as part of our continuing screening of plant extracts for activities, the extracts of a. glutinosa, f. excelsior and p. rhoeas have been screened for their antioxidant and antibacterial activities, as well as their general toxicity towards brine shrimps. among ...
background: a successful malaria elimination program calls for enough attention to parasite carriers, especially asymptomatic malaria, as well as the diagnosis and treatment of clinical cases. asymptomatic malaria is an infection that patients do not show any symptom; thus, these patients play critical role in the concept of an elimination program. the current investigation was conducted to e...
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background: activation of inflammatory cells can cause more chemicals induced-hepatotoxicity. aflatoxin b1 (afb1) is a fungal toxin that induces acute hepatotoxicity in humans and animals. this study was conducted to examine the effect of co-exposure lps and various aflatoxin b1 doses on the damage hepatic parameters in isolated perfused rat liver. methods: thirty-two male wistar rats (250-300g...
purpose lipocalin-2 (lcn2), a newer adipocyte-secreted acute phase protein, was recently reported to be correlated with potential effects on obesity and inflammation. the reaction of this protein to progressive exercise has not been evaluated yet. this study was designed to compare the serum lcn2 and high-sensitivity c-reactive protein (hs-crp) levels after participating in an acute bout of tre...
myeloperoxidase (mpo) and paraoxonase-1 (pon1) are inflammatory and anti-inflammatory enzymes, respectively that have been involved in the pathogenesis of coronary artery disease (cad). in this study we sought to evaluate the relations of mpo and pon1 with high density lipoprotein (hdl) mean size in patients with acute coronary syndrome (acs). collectively, 50 control subjects and 50 patients w...
results at high concentrations (40 and 100 μm), apoptosis was demonstrated and it was clearly more prominent in hepatocytes exposed to celecoxib loaded liposomes. conclusions our results showed that celecoxib loaded liposomes robustly induced apoptosis, an action that can potentially make it more relevant than the usual form for chemopreventive strategies and also may raise concerns about its t...
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