نتایج جستجو برای: pc mutation

تعداد نتایج: 331855  

Journal: :iranian journal of basic medical sciences 0
abdolvahab moradi infectious diseases research center, department of microbiology, school of medicine, golestan university of medical sciences, gorgan, iran sareh zhand infectious diseases research center, department of microbiology, school of medicine, golestan university of medical sciences, gorgan, iran amir ghaemi infectious diseases research center, department of microbiology, school of medicine, golestan university of medical sciences, gorgan, iran naeme javid infectious diseases research center, department of microbiology, school of medicine, golestan university of medical sciences, gorgan, iran masoud bazouri infectious diseases research center, department of microbiology, school of medicine, golestan university of medical sciences, gorgan, iran alijan tabarraei infectious diseases research center, department of microbiology, school of medicine, golestan university of medical sciences, gorgan, iran

objective(s): it has been reported that the mutation of the pre-core (pc) and basal-core promoter (bcp) may play an important role in the development of hbv-related hepatocellular carcinoma (hcc). in this study the pc and bcp mutations were investigated in chronic hbv patients. materials and methods:in this study, 120 chronic hbv patients from golestan, northeast of iran who were not vaccinated...

Abdolvahab Moradi Alijan Tabarraei, Amir Ghaemi, Masoud Bazouri Naeme Javid, Sareh Zhand

Objective(s): It has been reported that the mutation of the pre-core (PC) and basal-core promoter (BCP) may play an important role in the development of HBV-related hepatocellular carcinoma (HCC). In this study the PC and BCP mutations were investigated in chronic HBV patients. Materials and Methods:In this study, 120 chronic HBV patients from Golestan, Northeast of Iran who were not vaccinated...

Background and Objective: BRAF mutations were studied in various populations for prostate carcinoma (PC); however, mutations in BRAF gene are unusual compared to KRAS. Oncogenic activating of BRAF mutations were studied lately in almost 0%-10% of prostate cancer cases. Methods: In this retrospective study, we gathered 100 formalin-fixed ...

Journal: :jundishapur journal of microbiology 0
sareh zhand department of microbiology, school of medicine, golestan university of medical sciences, gorgan, ir iran chiman karami department of microbiology, school of medicine, golestan university of medical sciences, gorgan, ir iran ahmad hosseinzadeh adli department of microbiology, school of medicine, golestan university of medical sciences, gorgan, ir iran alijan tabarraei department of microbiology, school of medicine, golestan university of medical sciences, gorgan, ir iran behnaz khodabakhshi infectious diseases research centre, golestan university of medical sciences, gorgan, ir iran abdolvahab moradi department of microbiology, school of medicine, golestan university of medical sciences, gorgan, ir iran; department of microbiology, school of medicine, golestan university of medical sciences, gorgan, ir iran. tel: +98-9111772107, fax: + 98-1714440225

conclusions this study indicates that the rate of g1896a mutation at the pc region among hbeag negative patients, in the golestan province of iran, was similar to the average rate encountered in other parts of iran. the pc stop codon mutation was detected in 93.18% of hbeag negative patients. further studies with larger sample sizes are required to elucidate the exact role of these mutations in...

Journal: :Blood 1996
B Brenner A Zivelin N Lanir J S Greengard J H Griffin U Seligsohn

It is remarkable that certain patients with heterozygous protein C (PC) deficiency manifest venous thromboembolism (VTE), whereas others, particularly those belonging to families with homozygous PC deficiency, remain asymptomatic. The goals of the present study of a family, in which the proband had homozygous PC deficiency, were to identify members with and without VTE, to determine the mutatio...

Journal: :Intervirology 2014
Haimanti Bhattacharya Debdutta Bhattacharya Muruganandam Nagarajan Rajesh Reesu Subarna Roy Purushottaman Sugunan Attayur

The aim of this study was to explore the prevalence of basal core promoter (BCP) and precore gene (PC) mutations in hepatitis B virus (HBV) isolates among the Nicobarese tribe and their relationship with genotypes and HBeAg status. A total of 726 blood samples were collected from two villages of the Car Nicobar Island where mass vaccination was performed in the year 2000. HBV DNA was isolated a...

2017
Naveen Kumar Kansal

287 Indian Dermatology Online Journal | Volume 8 | Issue 4 | July‐August 2017 Sir, We read with great interest the informative case report “Pachyonychia congenita with late onset (PC tarda)” by Sravanthi et al. in the July‐August 2016 issue of the Journal.[1] However, we would like to emphasize certain points regarding the history and current classification system of this rare disorder of kerat...

Journal: :hepatitis monthly 0
rym ayari laboratory of immunology research center, kidney transplantation and immunopathology (lr03sp01), charles nicolle hospital, university of tunis el manar, tunisia +216-25462623, [email protected]; laboratory of immunology research center, kidney transplantation and immunopathology (lr03sp01), charles nicolle hospital, university of tunis el manar, tunisia +216-25462623, [email protected] yousr lakhoua-gorgi laboratory of immunology research center, kidney transplantation and immunopathology (lr03sp01), charles nicolle hospital, university of tunis el manar, tunisia +216-25462623, [email protected] lamjed bouslama borj cedria center for biotechnology, hammam lif, tunisia imen safar laboratory of immunology research center, kidney transplantation and immunopathology (lr03sp01), charles nicolle hospital, university of tunis el manar, tunisia +216-25462623, [email protected] fatma houissa kchouk laboratory of immunology research center, kidney transplantation and immunopathology (lr03sp01), charles nicolle hospital, university of tunis el manar, tunisia +216-25462623, [email protected] houda aouadi laboratory of immunology research center, kidney transplantation and immunopathology (lr03sp01), charles nicolle hospital, university of tunis el manar, tunisia +216-25462623, [email protected]

background in this study, we evaluated the prevalence of the most common mutations occurring in enhancer ii (enhii), basal core promoter (bcp), precore (pc), and core (c) regions of hepatitis b virus (hbv) genome. objectives we also investigated the correlation between hbv variants, their genotypes, and patients’ hbe antigen (hbeag: soluble shape of the capsid antigen) status patients and metho...

Journal: :Journal of clinical microbiology 2005
Therese L Waltz Salvatore Marras Gemma Rochford John Nolan Eugenia Lee Margherita Melegari Henry Pollack

The 1896 precore (PC) mutation is the most frequent cause of hepatitis B virus e-antigen (HBeAg)-negative chronic hepatitis B virus (HBV) infection. Detection of the 1896 PC mutation has application in studies monitoring antiviral therapy and the natural history of the disease. Identification of this mutation is usually performed by direct sequencing, which is both costly and laborious. The aim...

2015
Jinxin Li Qinghai Huang Liang Ge Jing Xu Xingjuan Shi Wei Xie Xiang Liu Xiangdong Liu

Paramyotonia congenita (PC) is a rare autosomal dominant neuromuscular disorder characterized by juvenile onset and development of cold-induced myotonia after repeated activities. The disease is mostly caused by genetic mutations of the sodium channel, voltage-gated, type IV, alpha subunit (SCN4A) gene. This study intended to systematically identify the causative genetic variations of a Chinese...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید