Peripheral neuropathy is characterized as a generalized, relatively homogeneous process affecting many peripheral nerves and predominantly affecting distal nerves. The epidemiology of peripheral neuropathy is limited since the disease presents with varying etiology, pathology, and severity. Toxic, inflammatory, hereditary, and infectious factors can cause damage to the peripheral nerves resulti...

Background: Diabetic Peripheral Neuropathy (DPN) is a common and difficult complication of diabetes poses significant burden to many diabetics the public health-care system. patients in rural areas have higher risk developing related complications inadequate access proper treatment especially low-income countries. Objectives: To determine prevalence diabetic peripheral neuropathy with Type II N...

OBJECTIVE The severity of peripheral neuropathy in diabetic patients varies for unclear reasons. Long-term use of metformin is associated with malabsorption of vitamin B(12) (cobalamin [Cbl]) and elevated homocysteine (Hcy) and methylmalonic acid (MMA) levels, which may have deleterious effects on peripheral nerves. The intent of this study was to clarify the relationship among metformin exposu...

This study aims to identify the effect of foot bath intervention on reducing symptoms peripheral neuropathy in patients undergoing chemotherapy. The method used is a quasi-experimental pre-test and post-test with control group design. Data was collected using Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT) questionnaire total sample 66 consisting 33 selected by consecutive s...

BACKGROUND The introduction of antiretroviral therapy (ART) has dramatically reduced the mortality rate of people living with HIV (PLHIV). However, complications of both HIV and ART, such as peripheral neuropathy currently affect PLHIV. The purpose of this study was to establish the prevalence of peripheral neuropathy of the lower extremity and, its association with demographic and health statu...

OBJECTIVE This study investigated the association between dietary intake of polyunsaturated fatty acids (PUFAs) and peripheral neuropathy in the U.S. population. RESEARCH DESIGN AND METHODS We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 1999-2004 for adults >or=40 years of age with diagnosed diabetes, an assessment of peripheral neuropathy, and reliable 24...

OBJECTIVES The aim of this study was to survey the level of self-reported physical activity in people with type 2 diabetes, with and without peripheral neuropathy. METHODS A sample of South Australian adults (n=481) 33 to 88 years of age who had type 2 diabetes, including 55 people with peripheral neuropathy, completed the International Physical Activity Questionnaire (IPAQ). Levels of self-r...

The frequency, characteristics and reversibility of bortezomib-associated peripheral neuropathy were evaluated in the phase III APEX (Assessment of Proteasome Inhibition for Extending Remissions) trial in patients with relapsed myeloma, and the impact of a dose-modification guideline on peripheral neuropathy severity and reversibility was assessed. Patients received bortezomib 1.3 mg/m(2) (days...

Diabetic foot ulcer (DFU) is one of the greatest thoughtful difficulties diabetes, negatively affecting patient's health and socioeconomic status. Around world, diabetes prevalence increasing in both developing developed countries. There are several measures place most countries to limit complications. This review summarizes pathogenic mechanisms that lead diabetic focuses on prevention managem...