The nuclear magnetic resonance spectra of phosphatidylethanolamines, phosphatidylcholines, phosphatidylserines, and sphingomyelin are discussed in terms of molecular structure. The factors influencing the band width of the protons of the polar head of phosphatidylcholines are surveyed. It is found that the band widths vary with solvent and that this variation can perhaps be correlated with the ...

Exosomes are small vesicles secreted from multivesicular bodies, which are able to stimulate the immune system leading to tumour cell eradication. We have analysed lipids of exosomes secreted either upon stimulation from rat mast cells (RBL-2H3 cells), or constitutively from human dendritic cells. As compared with parent cells, exosomes displayed an enrichment in sphingomyelin, but not in chole...

The compositions and physical states of the liver phospholipids of marine and freshwater fish adapted to relatively constant but radically different temperatures were investigated. Fish adapted to low temperature (5-10 degrees C) accumulated more unsaturated fatty acids than those in a warm (25-27 degrees C) environment. There were no measurable differences in the gross fatty acid compositions ...

Phospholipids are the main component of naturally occurring bilayers. These phospholipids include phosphatidylcholines (PC), phosphatidylethanolamines (PE) and phosphatidylserines (PS) [1]. The key common feature that bilayer-forming compounds share is their amphiphilicity ie., they have defined polar and non-polar regions. This is the reason the non-polar regions orientate themselves towards t...

More than 30 years ago, a calcium-dependent enzyme activity was described that generates N-acyl phosphatidylethanolamines (NAPEs), which are precursors for N-acyl ethanolamine (NAE) lipid transmitters, including the endocannabinoid anandamide. The identity of this calcium-dependent N-acyltransferase (Ca-NAT) has remained mysterious. Here, we use activity-based protein profiling to identify the ...