background: snow trout (schizothorax pelzami) is an economically important species endemic in the north east of iran. objectives:  the purpose of the present study was to investigate the reproduction cycle, time and temperature range of spawning. methods: the biometry of 243 fishes was measured and the ovarian development stages and plasma sex steroid hormones (testosterone, 17b- estradiol, pro...

The hormonal derivatives diethylstilbestrol, hexestrol, dienestrol, cortisone, estradiol-17a, estradiol-17/3, progesterone, and phloretin were compared with regard to their capacity to enhance carcinostasis in the presence of the niacin antagonist 6aminonicotinamide. Diethylstilbestrol and hexestrol were found to be more powerful than either estradiol-17/îor dienestrol. Phloretin, estradiol-17...

Two enzymes are responsible for the cleavage of pregnane side chains. A steroid-inducible oxygenase, in the presence of reduced nicotinamide adenine trinucleotide and molecular oxygen, catalyzes the conversion of progesterone into testosterone acetate. The latter ester is then hydrolyzed by an esterase to yield testosterone. The oxygenase has been partially purified and separated from the ester...

A number of synthetic and naturally occurring steroids were studied for competitive binding to two progesterone receptors, one in chick oviduct and another in human uterus. The results show a good correlation of relative (to progesterone) binding affinity with progestational activity as measured by subcutaneous Clauberg assay. 17a-Ethynyltestosterone and closely related compounds compete very w...

20a-Hydroxy-A4-pregnen-3-one-20p-3H can be detected after incubation of progesterone and estradiol-17a-3H with slices of female rat liver and rat ovaries, which proves the transfer of hydrogen from estradiol to progesterone. While 20oc-hydroxy-A4-pregnen-3-one is found only in very small amounts after incubation of progesterone with female rat liver slices the reduction at CzO increases 20-fold...

The changes of androgen output in the spermatic vein blood of anesthetized dogs were analyzed by gas chromatography following FSH and LH (HCG) administration . A definite increase of testosterone and DHEA was seen following LH administration . No significant increase of androst-4-ene-3, 17-dione was demonstrated , contrary to our expectation. 3H-testosterone as well as H3-DHEA was also isolated...

Biological activities of 17a-acetoxy-6-chloro-pregna-4,6-diene-3,20-dione (chlormadinone acetate ; CMA) were investigated in comparison with those of 17a-acetoxy-6a-methylpregnane-3,20-dione (medroxyprogesterone acetate ; MAP). CMA produced marked progestational activity either subcutaneously or orally in the uterine carbonic anhydrase test, and its relative potency is approximately 30 times th...

background: atrial fibrillation (af) is the most common cardiac arrhythmia and an independent risk factor for stroke among the elderly. a role for inflammation in the atrial remodeling as well as development and recurrence of af is known. objective: to compare il-17a between patients with different types of af and healthy individuals. methods: il-17a was measured in sera of 112 patients and 107...

Background: Atrial Fibrillation (AF) is the most common cardiac arrhythmia and an independent risk factor for stroke among the elderly. A role for inflammation in the atrial remodeling as well as development and recurrence of AF is known. Objective: To compare IL-17A between patients with different types of AF and healthy individuals. Methods: IL-17A was measured in sera of 112 patients and 107...