background: quaternary ammonium compounds (qac), which contain benzalkonium chloride as the most widely used agent, are employed as wound and skin antiseptics, as well as disinfectants in hospitals. the resistance mechanism to disinfectants is usually determine by genes which are related to resistance to quaternary ammonium compounds, namely, qace, qacδe1, qacδe1 that are found in gram-negative...

Quaternary ammonium compounds, effective as sanitizing agents for food plant equipment under certain conditions, are not well suited as sanitizers for water of high mineral content. Mueller and Seeley (1951) have demonstrated under controlled conditions that various metallic cations can decrease the germicidal action of a quaternary in solution. Knowledge of how such interference takes place co...

Tests to determine the potential use of a quaternary ammonium resin-triiodide complex as a sterilizing agent showed that it was an ineffective sporicide and that bactericidal activity was impaired by complex milieu.

Potassium channels have a very wide distribution of single-channel conductance, with BK type Ca(2+)-activated K(+) channels having by far the largest. Even though crystallographic views of K(+) channel pores have become available, the structural basis underlying BK channels' large conductance has not been completely understood. In this study we use intracellularly applied quaternary ammonium co...

The study of good nonregular fractional factorial designs has received significant attention over the last two decades. Recent research indicates that designs constructed from quaternary codes (QC) are very promising in this regard. The present paper shows how a trigonometric approach can facilitate a systematic understanding of such QC designs and lead to new theoretical results covering hithe...

The objective of this study was to answer the following question: are quaternary ammonium antibacterials suitable for dental materials? Reviewing the literature on quaternary ammonium compounds evidenced that this type of compounds is soluble in water. Our own findings also showed that they are well soluble in water and that their application as dental composites requires to check their solubil...