Extensive studies of the mixed lymphocyte interaction (MLI) 1 have shown it to be an immunologically specific proliferative reaction in which a large proportion of immunologically competent, predominately thymus-derived, circulating lymphocytes from nonimmunized donors recognize and respond to the presence of major histocompatibility (H) isoantigens in culture (1-7). Prior immunization of the c...

The increasing role of software for developing products and services requires that organizations align their software-related activities with high-level business goals. In practice, this alignment is very difficult and only little systematic support is available. GQM+Strategies is a method that aims at aligning organizational goals, strategies, and measurements at all levels of an organization ...

The recent development of regional climate models which can potentially produce long-term (multi-year to multi-decadal) simulations at high spatial resolution (5-50 km), opens a range of possibilities for interactive coupling with ecosystem, hydrology, ocean-sea-ice and chemistry models on the regional scale. Such coupling offers two primary advantages: (1) It is accomplished at scales more con...

abstract from historical view point geopolitical factors have encouraged the politicians to be ambitious. countries of the world by making use of geopolitical potentials try to maintain stability and promote their status in world affairs. among the countries of the persian gulf region qatar is one of those countries which in recent regional developments have had geopolitical dynamic and have pl...

Using the parenchymal marker technique in normal anesthetized dogs, we compared the dynamics of regional lung expansion between two ventilation strategies designed to increase mean thoracic volume. Dynamic hyperinflation (DH was produced by ventilating the lungs at a rate of 50 breaths/min and with a duty cycle of 0.5. Static hyperinflation (SH) was produced through the application of extrinsic...

The concept of eco-efficiency is here presented as a valuable contribution to a sustainable regional development in the European Union. Eco-efficiency and dematerialization strategies are more and more established at the business level where practical and easily understandable methods and management tools have been developed and applied in the past years and decades. On this (micro) level, case...

This paper investigates the evolution of regional disparity over the period 1980-2001, reviews the debate on its causes, discusses future development strategies, and draws relevant conclusions for policymakers. Our study confirms that overall regional disparity declined in the 1980s but increased in the 1990s. The gap between the inland and coastal regions was the dominant contributor to the ov...

Introduction: Immunization has been shown to be the most successful and cost-effective public health intervention in the 20 century. In the developing world, it does not only prevent about three million child deaths annually, but also has the potential to prevent additional two million deaths if coverage improves. However, immunization coverage has remained low in Nigeria although vaccines are ...