Abstract In memory of Jonathan Williams, a valued colleague incisive intellect (and regarded by undergraduates as ‘the better-looking Prof. Williams’ in the Department). Bromomethyloxiranone has much larger repertoire molecular acrobatics than previously recognised: conformational isomerism, degenerate rearrangement that exchanges O atoms α-lactone ring, and epimerisation, all which occur with ...

Despite many previous important contributions to the characterization of the liquid-liquid phase behavior of ionic liquids (ILs) plus water systems, a gap still exists as far as the effect of isomers (of ILs) is concerned. Therefore, in this work, a comprehensive study of the liquid-liquid equilibria between water and isomeric pyridinium-based ionic liquids has been performed. Atmospheric press...

Background: So-called heterotaxy, better called bodily isomerism, is associated with increased frequency of thrombocytosis and thromboembolic events in childhood. This is likely mediated by splenic dysfunction present with isomerism. Data for adults with isomerism is lacking with a paucity of data regarding thrombosis and isomerism. This study aimed to determine the risk of thrombocytosis and t...

Fullerenes are reactive as dienophiles in Diels–Alder reactions. Their distinctive molecular shape and properties result interesting sometimes elusive reaction patterns. Herein, to contribute the understanding of fullerene reactivity, we evaluate energies reactions for cycloadditions C60, C70, IC60MA with anthracene (Ant), by means DFT computational analysis vacuum solution. The methods used sh...

INTRODUCTION To present the characteristics and spectrum of associated anomalies in right- and left-sided isomerism in our local population and to assess the possibility of using stomach-distance ratio (SDR) of less than 0.34 as a diagnostic tool to predict right atrial isomerism. MATERIALS AND METHODS This was a retrospective study of fetuses in our department over a period of 8 years with p...

Right atrial isomerism or left atrial isomerism is frequently diagnosed as situs ambiguous without further discrimination of the specific morbid anatomy. Thirty six cases of right atrial isomerism and seven cases of left atrial isomerism were collected from the records and pathological museum at the National Taiwan University Hospital. There was a necropsy report for 18 cases. In all patients o...

OBJECTIVE Left isomerism, also called polysplenia, is a laterality disturbance associated with with paired leftsidedness viscera and multiple small spleens. Left isomerism, heart congenital abnormalities and gastrointestinal malformation are strongly associated. METHODS We present a case of prenatal diagnosis of left isomerism in a fetus with a structurally normal heart. CONCLUSION Left iso...

Heterotaxy is defined as an abnormality where the internal thoraco-abdominal organs demonstrate abnormal arrangement across the left-right axis of the body. This broad term includes patients with a wide variety of very complex cardiac lesions. Patients with heterotaxy can be stratified into the subsets of asplenia syndrome and polysplenia syndrome, or the subsets of heterotaxy with isomerism of...

We introduce several series of novel ZE-isomerism descriptors derived directly from two-dimensional molecular topology. These descriptors make use of a quantity named ZE-isomerism correction, which is added to the vertex degrees of atoms connected by double bonds in Z and E configurations. This approach is similar to the one described previously for topological chirality descriptors (Golbraikh,...