Streptococcal bacteria are among dangerous human pathogens with major prevalence worldwide. A good vaccine against streptococcal bacteria should have epitopes that confer protection from infection by different streptococcal bacteria types. we aimed was to recognize the most immunogenic and conserved epitopes of streptococcal bacteria, which could be a potential candidate for vaccine development...

sydenham’s chorea is a delayed complication of group aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.it is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. it is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with sydenham’schorea produce antibodies that cross reac...

conclusions although lap had good performance in early diagnosis of gas, a combination of clinical findings, including tonsillar exudates, petechiae with results of rapid antigen test or culture is necessary for clinician judgment. throat culture is the gold standard test for detecting group a streptococcal infection, but rapid test is a good replacement for culture. objectives the aim of this ...

newborns’ bacterial infections due to group b streptococcus (gbs) happen in two forms including early-onset disease or late-onset disease. in this paper, we report a case of early-onset gbs infection in a male infant. a 22-year-old primigravid woman delivers a term normal looking male infant. nasal flaring, grunting, and poor feeding presented soon after birth. an empiric treatment with intrave...

Sydenham’s chorea is a delayed complication of group Aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.It is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. It is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with Sydenham’schorea produce antibodies that cross reac...

The group A Streptococcus is the most common bacterial cause of pharyngitis. Although most cases of streptococcal pharyngitis are managed by primary care providers, the otolaryngologist is often consulted to assist in the management of patients with persistent sore throat, chronic streptococcal carriage, recurrent streptococcal pharyngitis, or complications of streptococcal infection. This arti...

The nature of the mitogenic activity of pyrogenic streptococcal exotoxin B, also known as streptococcal cysteine protease, has been debated in the literature. Streptococcal exotoxin B has been shown to cleave interleukin-1beta precursor and create biologically active interleukin-1beta, a major cytokine mediating inflammation and shock. This activity could mimic the mitogenicity and cytokine rel...

The question of whether hypersensitivity to streptococcal antigens plays a role in the pathogenesis of the nonsuppurative sequelae of streptococcal infections remains at present unclear. As a first step in the approach to this question, the degree of cellular reactivity of peripheral blood leucocytes to streptococcal antigens was investigated in a number of rheumatic fever patients, patients wi...