the previous studies have been suggested that to tolerance,sensitivity and pain threshold are different between men and women.these differences can be affected by various factors.in this study,the effect of gonadectomy on gender differences in thermal pain sense threshold was tested hot plate method in rats.therefore the reaction time(the delay occurred in response to thermal stimulus)at zero,1...

a b s t r a c t there are three types of nerve fibers that are involved in the transmission of pain stimuli: c fibers (slower fibers) for thermal, mechanical and chemical stimuli, a-delta fibers for thermal or mechanical stimuli and a-beta fibers for touch stimuli. clinically, this is crucial in making an accurate assessment of the pain level experienced by a suffering patient, in indicating th...

This study evaluated relationships between irritable bowel syndrome (IBS) pain, sympathetic dysregulation, and thermal pain sensitivity. Eight female patients with diarrhea-predominant IBS and ten healthy female controls were tested for sensitivity to thermal stimulation of the left palm. A new method of response-dependent thermal stimulation was used to maintain pain intensity at a predetermin...

introduction: pemphigus vulgaris (pv) is a chronic, serious autoimmune mucocutaneous bullous disease. oral lesions in pv may be extremely painful. this pain may adversely affect the patients’ oral intake and quality of life. this before-after clinical trial was designed to assess the pain relieving effects of single session of non-ablative, non-thermal co2 laser therapy (ntclt) in oral lesions ...

BACKGROUND Recent studies have suggested an association between genotypes affecting the expression of the serotonin transporter and thermal pain perception and the thermal grill. The aim of this study was to investigate differences in thermal and mechanical pain perception and the thermal grill in two groups of healthy volunteers according to their genotype, associated with either high (n = 40)...

It is still unclear whether the quality of painful thermal sensation is determined only by conduction in specific, dedicated nociceptive channels (i.e. C or Adelta nociceptors) or whether it is a result of integrated activity in both nociceptive and non-nociceptive systems. To evaluate this question, we conducted quantitative and qualitative somatosensory testing in spinal cord injury subjects ...