نتایج جستجو برای: tlr2 mrna

تعداد نتایج: 157013  

Ali Roohbakhsh, Ali Shamsizadeh, Amir Moghadam-ahmadi Elham Hakimizadeh Gholamreza Bazmandegan, Hossein Rezazadeh, Iman Fatemi Mehdi Shariati, Mohammad Allahtavakoli, Mohammad Kazemi Arababadi, Mohammad Reza Hajizadeh

Objective(s): Stroke is known as a main cause of mortality and prolonged disability in adults. Both transient receptor potential V1 (TRPV1) channels and toll-like receptors (TLRs) are involved in mediating the inflammatory responses. In the present study, the effects of TRPV1 receptor activation and blockade on stroke outcome and gene expression of TLR2 and TLR4 were assessed following permanen...

Journal: :reports of biochemistry and molecular biology 0
mohsen tehrani immunobiochemistry lab, immunology research center, bu-ali research institute, mashhad, iran abdol-reza varasteh immunobiochemistry lab, immunology research center, bu-ali research institute, mashhad, iran mohammad reza khakzad zakaria research center, azad university of mashhad, mashhad, iran majid mirsadraee zakaria research center, azad university of mashhad, mashhad, iran mojtaba sankian tel: +98 511-7112410; fax: + 98 511- 7112616

background: recently, reports have indicated a role for the membrane form of toll-like receptor 2 (tlr2) in asthma pathogenesis. in this study we examined soluble tlr2 levels in serum and sputum of asthmatic and healthy subjects. methods: serum and sputum samples were obtained from 33 asthmatic and 19 healthy subjects. the asthmatics were classified into four groups according to the global init...

قرارگیری در هوای آلوده بر سیستم عصبی مرکزی تأثیرگذار است و به التهاب و تخریب عصبی منجر می‌شود. هدف از پژوهش حاضر بررسی تأثیر تمرین هوازی و هوای آلوده به ذرات کربن سیاه بر بیان mRNA ژن گیرندۀ شبه تول 2و 4 (TLR4 و TLR2 ) در هیپوکمپ مغز موش‌ها بود. 24 سر موش نر نژاد ویستار به‌طور تصادفی در چهار گروه الف) کنترل، ب) آلودگی، ج) تمرین و د) تمرین- آلودگی قرار گرفتند. موش‌های گروه‌های ب و د به مدت چهار ...

Journal: :iranian journal of allergy, asthma and immunology 0
ai-li li key laboratory of dairy science, ministry of education, college of food sciences, northeast agriculture university,  xiangfang district, harbin, heilongjiang, china yi-qiao sun key laboratory of dairy science, ministry of education, college of food sciences, northeast agriculture university,  xiangfang district, harbin, heilongjiang, china peng du key laboratory of dairy science, ministry of education, college of food sciences, northeast agriculture university,  xiangfang district, harbin, heilongjiang, china xiang-chen meng key laboratory of dairy science, ministry of education, college of food sciences, northeast agriculture university,  xiangfang district, harbin, heilongjiang, china ling guo key laboratory of dairy science, ministry of education, college of food sciences, northeast agriculture university,  xiangfang district, harbin, heilongjiang, china shuang li key laboratory of dairy science, ministry of education, college of food sciences, northeast agriculture university,  xiangfang district, harbin, heilongjiang, china

our previous study reported that lactobacillus acidophilus ( l.acidophilus )  key laboratory of dairy science  (klds) 1.0738 had an effective impact on inhibiting β-lactoglobulin (β-lg) allergy. this study further investigated the anti-allergic activity of peptidoglycan (pgn) isolated from klds 1.0738. this study aimed to assess whether toll-like receptor 2 (tlr2)/nf-kappab (nf-κb) signaling ac...

Abdolreza Varasteh, Ahmad Saffari, Farhad Salari, Mohammad Reza Khakzad, Mojtaba Meshkat, Mojtaba Sankian, Niloofar Mohamadpour,

Background: It is not yet known which types of Toll-like receptors (TLRs) are most effective in Helicobacter pylori (H. pylori) recognition. It is also not known which gastric zones have the most prominent roles in TLR-mediated bacterial recognition. The aim of this work was to analyze the expression of TLR2 and TLR4 in biopsy specimens from H. pylori-infected patients. Methods: Thirty-eight...

Abdol-Reza Varasteh, Majid Mirsadraee, Mohammad Reza Khakzad, Mohsen Tehrani, Mojtaba Sankian,

Background: Recently, reports have indicated a role for the membrane form of Toll-like Receptor 2 (TLR2) in asthma pathogenesis. In this study we examined soluble TLR2 levels in serum and sputum of asthmatic and healthy subjects. Methods: Serum and sputum samples were obtained from 33 asthmatic and 19 healthy subjects. The asthmatics were classified into four groups according to the Global I...

Journal: :hepatitis monthly 0
mahdi dehghan-manshadi immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran hossein hadinedoushan immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran; immunology department, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran; immunology department, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran. tel: +98-3536285406; +98-9133576620, fax: +98-3536238561 mohammad kazem amirbaigy gastrology department, faculty of medicine, shahid sadoughi hospital, shahid sadoughi university of medical sciences, yazd, ir iran fateme zare immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran gilda eslami parasitology and mycology department, shahid sadoughi university of medical sciences, yazd, ir iran seyyed ali mirghanizade-bafghi immunology department, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran

conclusions our findings showed that hcv infection could lead to increased expression level of tlr7 mrna in peripheral blood cells of hcv infected samples. the viral load and genotypes of hcv did not affect the mrna expression levels of tlr2 and tlr7. background hepatitis c virus (hcv) is an important human pathogen affecting an estimated 120 – 170 million individuals in the world. toll-like re...

Journal: :Journal of immunology 2000
T Wang W P Lafuse B S Zwilling

Recent studies have implicated Toll-like receptors (TLR), especially TLR2 and TLR4, as sentinel receptors that signal the interaction of macrophages with bacterial pathogens via a NF-kappaB-mediated pathway. The regulation of TLR gene expression, however, has not been intensively studied. Here, we report that TLR2 mRNA was induced following infection of murine macrophages with Mycobacterium avi...

A. Baranwal A. Chauhan A. K. Sharma A. Sonwane, M. Panigrahi

The present study was conducted to quantify and compare TLR2 (toll-like receptor 2) activity in monocyte-derived macrophages of zebu (Tharparkar) and crossbred (Holstein-Friesian × Jersey × Brown Swiss × Hariana) cattle. The cells were either induced with Pam3CSK4 or kept as control. The TLR2 activity was quantified in terms of IκB-α inhibitory subunit (NFKBIA) messenger RNA (mRNA) copies...

Journal: :Molecular Medicine Reports 2021

Toll‑like receptor (TLR) 2/4 serves an important regulatory role in nerve tissue injury. However, the downstream and potential mechanisms remain to be elucidated. The present study was designed investigate roles of TLR2/4‑major myeloid differentiation response gene 88 (MyD88)‑NF‑κB signaling pathway development intracranial aneurysm. expression TLR2, TLR4 MyD88 blood normal controls patients wi...

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