BACKGROUND Current guidelines consider aortic valve replacement reasonable in asymptomatic patients with very severe aortic stenosis (AS); however, the definition of very severe AS based on peak aortic jet velocity (Vmax) remains unclear with a 5-m/s cutoff in US guidelines and 5.5 m/s in European guidelines. Because ≈20% of patients with severe AS and preserved left ventricular ejection fracti...

We have investigated the effects of methanol, acetonitrile, dimethyl sulphoxide or dioxane on enzyme kinetic parameters (Km and Vmax) p-nitrophenol hydroxylation, phenacetin deethylation metoprolol metabolism in rat liver microsomes, at different solvent concentrations. In case methanol (0.1 %-0.75 % v/v) (0.01 %-0.075 showed 1.3 2.5-fold increase respectively, Km with a less marked effect Vmax...

We studied the relation of the maximal upstroke velocity (Vmax) of action potentials to the peak sodium current (INa) under voltage clamp in single, internally perfused, canine cardiac Purkinje cells under conditions that ensured membrane action potentials due only to INa. Three different methods of altering sodium channel availability were investigated: voltage-dependent inactivation, tetrodot...

In this study, nonlinear finite element (NLFE) analysis is conducted to determine the maximum shear capacity (Vmax) of stiffened steel plate walls (SSPSW) with rectangular openings. Results a wide range parametric study are presented using developed response surface method (RSM), which quantified effect prominent input variables on predicted SSPSW. The studied parameters, evaluated by different...

Background: Paralympic powerlifting (PP) is performed on a bench press, aiming to lift as much weight possible in single repetition. Purpose: To evaluate thermal asymmetry and dynamic force parameters with 45 80% 1 Repetition Maximum (1 RM) PP athletes. Methods: Twelve elite male athletes were evaluated before after training session regarding skin temperature (thermography) indicators (Average ...

We studied the effect of increasing the rate of stimulation on the maximum rate of rise of the action potential upstroke (Vmax) in guinea pig papillary muscles at various resting membrane potentials and after the addition of quinidine and lidocaine to the perfusate. Increasing rate caused a decrease in Vmax due to interaction of three factors: (1) a metabolic factor, presumably resetting of the...

Min. hip  – – 0.12 0.11 0.06 0.22 – – – – – – Min. knee  – – – – 0.15 0.28 – – 0.11 0.17 0.10 0.17 Min. ankle  0.06 –0.06 – – 0.10 0.30 0.10 –0.05 – – – – Min. MTP  0.15 0.20 – – 0.05 0.17 0.10 0.09 – – – – Min. rotation  – – – – – – – – 0.14 0.22 0.15 0.17 Total  swept hip – – – – 0.09 0.16 – – – – – – Total  swept knee – – – – – – – – 0.08 0.17 0.07 0.20 Total  swept ankle 0.10 –0.04 ...