synthesis of 4,4′-(arylmethylene)bis(1h-pyrazol-5-ols) via multi-component reactions by using silica-bonded sulfamic acid derivatives
چکیده
the one-pot, multi-component synthesis of 4,4′-(arylmethylene)bis(1h-pyrazol-5-ols) by tandem knoevenagel-michael reaction of phenylhydrazine, ethyl acetoacetate and aldehydes in the presence of silica-bonded n-propylpiperazine sulfamic acid (sbppsa) as a recyclable solid acid catalyst was reported. sbppsa showed much the same efficiency when used in consecutive reaction runs.