Vahid Pirhajati Mahabadi

Department of Anatomy, Tehran University of Medical Science, Tehran, Iran

[ 1 ] - Combination of Stem Cell Mobilized by Granulocyte-Colony Stimulating Factor and Human Umbilical Cord Matrix Stem Cell: Therapy of Traumatic Brain Injury in Rats

Objective(s) Clinical studies of treating traumatic brain injury (TBI) with autologous adult stem cells led us to examine the impression of a combination therapy. This was performed by intravenous injection of human umbilical cord matrix stem cell (hUCMSC-Wharton,s jelly stem cell) with bone marrow cell mobilized by granulocytecolony stimulating factor (G-CSF) in rats injured with cortical com...

[ 2 ] - In Vitro Differentiation of Neural Stem Cells into Noradrenergic-Like Cells

Neural stem cells (NSCs) as a heterogeneous multipotent and self- renewal population are found in different areas in the developing mammalian nervous system, as well as the sub-ventricular zone (SVZ) and the hippocampus of the adult brain. NSCs can give rise to neurons, astrocytes and oligodendrocytes. The aim of this study was to differentiate neural stem cells into noradrenergic–like cells in...

[ 3 ] - A case of ciprofloxacin-associated Achilles tendinitis

Achilles tendinitis is a rare adverse effect of the fluoroquinolone antibiotics. Fluoroquinolone antibiotics have widespread usage for treatment of Gram-negative-related infections particularly urinary tract and respiratory infections. Due to the prevalent usage of this family of antibiotics, it is necessary to be careful about their side effects including Achilles tendinitis, which can ensue t...

[ 4 ] - Effects of bilateral lesion of the locus coeruleus on the sleep-wake cycle in the rat

Introduction: Noradrenergic cells in LC participate in the process of cortical activation and behavioral arousal. The evidence suggests that locus ceoruleus (LC) plays an important role in the sleep-wake cycle. The aim of this study was stereological estimation of cavity caused by lesion and assessment of sleep stages after bilateral lesion of the LC. Materials and Methods: Male Wistar rats we...

[ 5 ] - Selenium nanoparticles role in organ systems functionality and disorder

Extensive research on the nutritional and medical application of selenium nanoparticles (SeNPs) was performed in past decades. Besides nutritional values, new characteristics such as antibacterial and anticancer properties depict a bright future for high Selenium (Se) consumption in the coming years. Se is essential for the proper functioning of most of the m...

[ 6 ] - Anti-inflammatory and anti-apoptotic effects of hyperbaric oxygen preconditioning in a rat model of cisplatin-induced peripheral neuropathy

Objective(s): Cisplatin-induced peripheral neuropathy is a debilitating side effect in patients receiving this drug.  Recent studies suggest hyperbaric oxygen (HBO) therapy as a new treatment approach for models of neural injury. The aim of the current study was to determine the protective effects of HBO preconditioning against peripheral neuropathy induced by Cisplati...