نتایج جستجو برای: that his goal

تعداد نتایج: 6543519  

2012
Marina V Atzingen Mônica L Vieira Rosane Oliveira Renan F Domingos Renata S Mendes Aline T Barros Amane P Gonçales Zenaide M de Morais Silvio A Vasconcellos Ana LTO Nascimento

Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira. The whole-genome sequence of L. interrogans serovar Copenhageni together with bioinformatics tools represent a great opportunity to search for novel antigen candidates that could be used as subunit vaccine against leptospirosis. We focused on six genes encoding for conserved hypothetical proteins predicted to be exported to ...

2010
Ronald K. June Khirud Gogoi Akiko Eguchi Xian-Shu Cui Steven F. Dowdy

Intracellular delivery of functional macromolecules using peptide transduction domains (PTDs) is an exciting technology with both experimental and therapeutic applications. Recent data indicate that PTD-mediated transduction occurs via fluid-phase macropinocytosis involving an intracellular pH drop to approximately 5. Nitrilotriacetic acid (NTA)-coordinated metals avidly bind hexahistidine-tagg...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم انسانی 1389

abstract: sayyed mohammad tabatabaee is accounted as one of the effective persons in iran contemporaneoushistory and his role in the events of iran constitution revolution is inevitable. sayyed mohammad tabatabaee from the time of naser al din shah qajar and arrival to iran, informed of the advantages and the basis of constitution, was in the thought of making the iran rule as a constituti...

2012
Gregorio León-García Alfredo Santana Nicolás Villegas-Sepúlveda Concepción Pérez-González José M Henrríquez-Esquíroz Carlota de León-García Carlos Wong Isabel Baeza

BACKGROUND The ATP7A gene encodes the ATP7A protein, which is a trans-Golgi network copper transporter expressed in the brain and other organs. Mutations in this gene cause disorders of copper metabolism, such as Menkes disease. Here we describe the novel and unusual mutation (p.T1048I) in the ATP7A gene of a child with Menkes disease. The mutation affects a conserved DKTGT1048 phosphorylation ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید مدنی آذربایجان - دانشکده ادبیات و علوم انسانی 1392

when we return to the concept of poetry and the age-old discussion about the uselessness or the usefulness of the poets to the private and public state of human beings, originating from plato and aristotles views about poets respectively, there emerges the question of the role of poetry in human beings lives. in the same manner, with the advance of technology and the daily progress and improvem...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده علوم انسانی 1393

in this research the focus of the researcher is on the influence of american myths that have long been held and offered by the american culture and ideologies. sam shepard is conceived to be one of the greatest playwrights of the contemporary american theater. in his works he depicts broken characters who are struggling to keep up with the national expectations but are ceaselessly borne back to...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان - دانشکده علوم انسانی 1392

the present study is an attempt to investigate the potential impact of inspirational quotes on improving english abstract vocabulary recall. to achieve this goal, a multiple choice language proficiency test of 60 items including vocabulary and grammar component was administered to a sample of 63 second-semester male and female students whose age ranged between 17 to 22 and they were studying en...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز 1382

‏‎translation as a comunicative process is always said to be associated with various aspects of meaning loss or gain. subtitling as a mode of translating, due to special discoursal and textual conditions imposed upon it, is believed to be an obvious case of this loss or gain. presenting the spoken sound track of a film in writing and synchronizing the perception of this text by the viewers with...

Journal: :Endocrinology 2003
Louis D Payet Xiu-Hong Wang Robert C Baxter Sue M Firth

Both the amino-terminal and carboxyl-terminal domains of IGF binding protein (IGFBP)-3 are believed to contribute to high-affinity IGF binding. To investigate cooperativity in IGF binding by these domains, we expressed IGFBP-3 fragments 1-88 (NBP-3) and 185-264 (CBP-3) as FLAG and hexahistidine-tagged fusion proteins, respectively. IGF-I and IGF-II bound to NBP-3 poorly and to CBP-3 with modera...

Journal: :European journal of biochemistry 2000
K Kosemund I Geiger H Paulsen

The major light-harvesting chlorophyll a/b-binding protein (Lhcb1,2) of photosystem II is inserted into the thylakoid via the signal recognition particle dependent pathway. However, the mechanism by which the protein enters the membrane is at this time unknown. In order to define some topographical restrictions for this process, we constructed several recombinant derivatives of Lhcb1 carrying h...

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