Stem cells generate the differentiated progeny cells of adult tissues. Stem cells in the Caenorhabditis elegans hermaphrodite germline are maintained within a proliferative zone of ∼230 cells, ∼20 cell diameters in length, through GLP-1 Notch signaling. The distal tip cell caps the germline and supplies GLP-1-activating ligand, and the distal-most germ cells that occupy this niche are likely se...

Background and purpose - The loss of bone mineral in the proximal femur following hip arthroplasty may increase the fracture risk around uncemented stems. We hypothesized that the surgical approach to the hip might influence bone mineral changes around the femoral stem in patients with a femoral neck fracture (FNF). Patients and methods - This was a pre-specified subgroup analysis (n = 51) of a...

INTRODUCTION Melanosis coli is a benign lesion affecting the mucosa of the large intestine. There is a relationship between the presence of melanosis and anthraquinone laxative use. Melanosis coli is also observed in patients with colon cancer, but there is doubt whether these two conditions are related. AIM To analyze the correlation between melanosis and colon cancer. MATERIAL AND METHODS...

This study represents an effort to construct a learning framework for knowledge building and collective wisdom advancement in a virtual learning community (VLC) from the perspectives of system wholeness, intelligence wholeness and dynamics, learning models, and knowledge management. It also tries to construct the zone of proximal development (ZPD) of VLCs based on the combination of Vygotsky’s ...

The vertebrate limb is one of the most relevant experimental models in which to analyse cell-cell signalling during patterning of embryonic fields and organogenesis. Recently, the combination of molecular and genetic studies with experimental manipulation of developing limb buds has significantly advanced our understanding of the complex molecular interactions coordinating limb bud outgrowth an...

Benthic foraminifera assemblages from two fjords of Svalbard—Kongsfjorden and Krossfjorden in the High Arctic—have been studied. The show three characteristic fjords’ glacial proximal, middle distal parts. Cassidulina reniforme– Elphidium clavatum, Textularia spp. assemblage dominates fauna near glacier proximal that indicates increased sedimentation meltwater runoff; a Nonionellina labradorica...

Objective- To measure statistically bone cortex to diameter  (C/D) ratio in metocarpo/metatarsal and proximal phalanges in camel. This ratio may be used in diagnosing possible metabolic and nutritional diseases in camel. Design- Experimental study. Animals- Twelve camel limbs (6 fore limbs & 6 hind limbs)      Procedures- This study was conducted on dorsopalmar/dorsoplantar radiographs of t...