Long protocol of Gonadotropin-Releasing Hormone-analougue (GnRH-a) can result in the formation of ovarian cyst by the transient initial stimulatory effect which increases the levels of both follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These cysts require surgical drainage or result in poor ovarian response. Ovarian cyst formation can be prevented by taking oral contraceptive...

The Vehicle Scheduling Problem (VSP) is the task of building an optimal set of rotations (vehicle schedule), such that each trip of a given timetable is covered by exactly one rotation. The restrictions and optimization criteria may differ from one problem setting to another. For multi-depot, multi-vehicle-type VSP for bus transit, each one-day rotation must end at the depot of start and is to ...

Abstract This paper develops new solution procedures for the order picker routing problem in U-shaped picking zones with a movable depot, which has so far only been solved using simple heuristics. The presents first exact approach, based on combinatorial Benders decomposition, as well heuristic approach dynamic programming that extends idea of venerable sweep algorithm. In computational study, ...

The aims of this retrospective study were to evaluate the efficacy of different steroid formulations (depot vs oral) and if the continuous administration of steroids throughout and beyond a CHOP protocol might improve the survival time and rate of cats with mediastinal lymphoma. The medical records of client-owned cats diagnosed with mediastinal lymphoma were reviewed at two veterinary referral...

N P-hard problem as a total distance minimization problem. Natural extension of the notorious traveling salesperson problem (TSP) with… Delivery vehicles (homogeneous or heterogeneous fleet) have a limited capacity. One or more nodes in the graph (single depot vs. multi-depots) are designated as origins of routes. Each route should emanate from such an origin node. The rest of the nodes are ide...