Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal dominantly inherited disorder that affects peripheral nerves by repeated focal pressure. HNPP can be diagnosed by clinical findings, electrodiagnostic studies, histopathological features, and genetic analysis. Ultrasonography is increasingly used for the diagnosis of neuromuscular diseases; however, sonographic feat...

There is a need for practitioners to be knowledgeable about potential complications from nerve conduction studies and needle electromyography as well as to know how to reduce the risk of such complications. Since a summary of risks inherent to electrodiagnostic (EDX) medicine was first published over one decade ago, publication of additional literature and technological advances warrant reasses...

Duchenne de Boulogne was among the first to investigate neuromuscular diseases. He stimulated muscle and nerve with moistened surface electrodes, thereby avoiding tissue necrosis. Technique and self-designed equipment are discussed in his first major work de l'électrisation localisée. During his 30 years of practice, he examined several hundred patients with poliomyelitis. With electrodiagnosti...

Congenital insensitivity to pain with anhidrosis is a rare disease with an autosomal recessive inheritance. The patients present in early childhood with frequent episodes of fever and absence of sweating. Painless fractures, bruises and cuts are quite common. Defective lacrimation and mental retardation are strongly diagnostic. Repeated injuries often lead to a reduced life expectancy. The diag...

UNLABELLED Guillain-Barre Syndrome (GBS) has an unpredictable clinical course with up to 30% of patients requiring assisted ventilation during the course of their illness. Successful management mandates anticipation, prompt recognition and optimal treatment of neuromuscular respiratory failure in GBS. AIMS To identify clinical and electrodiagnostic predictors of neuromuscular respiratory para...