Background: Expression of virus coat protein (CP) in Escherichia coli often leads to production of partially folded aggregated proteins which are called inclusion bodies. Grapevine fanleaf virus (GFLV) is one of the most serious and widespread grapevine virus diseases around the world and in Iran.Objective: The main objective of this study was to find a s...

BACKGROUND The capacity for herpesvirus to cause disease in cetaceans is unclear and may be varied depending on the different conditions of individuals and between different species. Kidney pathology and intralesional virus-associated infection have been rarely reported in cetaceans. RESULT On April 2004, an old adult male Blainville's beaked whale (Mesoplodon densirostris) 420 cm long with a...

Background BK virus (BKV) is the cause of nephropathy. Because BKV nephropathy can progress to graft loss, early diagnosis of BKV infection is very important. In this study, we aimed to investigate the utility of quantifying cells with intranuclear inclusion bodies (decoy cells) in urinary sediment for the screening and monitoring of BKV infection in renal transplant recipients at our hospital....

Background: Hyperuricemia contributes to kidney injury, characterized by tubular injury with epithelial–mesenchymal transition (EMT). Wnt5a/Ror2 signaling drives EMT in many kidney pathologies. This study sought to evaluate the involvement of Wnt5a/Ror2 in hyperuricemia-induced EMT in kidney tubular injury.Methods: A hyperuricemia model was performed in male Swiss background mice (3 months old,...

  The first time the white spot disease (WSD) and IHHNV were reported in Iran was in 2004 and 2008, respectively in Bushehr Province. In Sistan and Balochestan province only the WSD was reported in 2008.The aim of this study was detecting these two viral diseases in these provinces, during December 2009 to April 2010. A total of 364 samples were collected according to suspected gross signs from...

The importance of N-terminal regions of nuclear hormone receptors in transcriptional regulation is increasingly recognized. As variant VDR gene transcripts indicated possible N-terminally extended receptors, we investigated their natural occurrence, transactivation capacity, and subcellular localization. A novel 54-kDa VDRB1 protein, in addition to the previously recognized 48-kDa VDRA form, wa...

case history: equine coital exanthema caused by equine herpesvirus 3 (ehv3) was reported in 1900. at the present time, it has become epidemic among horses. the virus could be transmitted via insemination, iatrogenic, and it basically infects the squamous epithelium of the epidermis. clinical presentation: in the first week of january 2012 two mature male horses and a mare were imported from net...

the karyotype of zagros tooth-carp, aphanius vladykovi (coad) has been investigated byexamining metaphase chromosomes spreads obtained from gill epithelial and kidney cells. the diploidchromosome number of this species was 2n=48. the karyotype consisted of 8 submetacentric and 40subtelocentric chromosomes (8sm+40 st). the arm number (nf) was 28. sex chromosomes werecytologically indistinguishab...