In eukaryotes, the initiation of DNA synthesis requires the assembly of a pre-replicative complex (pre-RC) at origins of replication. This involves the sequential binding of ORC (origin-recognition-complex), Cdc6 and MCM proteins, a process referred to as licensing. After origin firing, the Cdc6 and MCM proteins dissociate from the chromatin, and do not rebind until after the completion of mito...

introduction: the production of smear layer during canal instrumentation is thought to increase coronal microleakage even after canal obturation. previous studies have shown that the type of irrigant does not necessarily affect the seal of the obturation. our study aimed to evaluate the effect of three irrigation solutions (mtad, citric acid and edta/naocl) on the coronal microleakage of root c...

This study was conducted to evaluate the effects of dietary supplement-ation of rosemary essential oils (REO) and zinc (as zinc sulfate) on performance, egg quality traits, and some serum biochemical metabolites of laying hens. A total of 144 44-weeks-old Lohmann LSL-Lite laying hens were randomly allocated into four treatments, each comprising six replicates of six birds. The first group was s...

Egg laying in the pond snail Lymnaea stagnalis is triggered by a discharge of the neuroendocrine caudodorsal cells (CDCs). The CDCs expresses three different caudorsal cell hormone (CDCH) genes. This gene family expresses, in total, 11 different peptides among which is the ovulation hormone. Besides the CDCs, the CDCH gene family is expressed in other central and peripheral neurons. In this stu...

background and objective: evaluation of degenerative changes of motoneurons and their related synapses can be useful in understanding the mechanisms of neurodegenerative diseases and their potential treatment. the present electron microscopic and immunohistochemical study investigates the axotomy-induced changes of adult spinal motoneurons up to 3 months following sciatic nerve transection. mat...

Healthy aging is characterized by a gradual decline in cognitive control and inhibition of interferences, while emotional control is either preserved or facilitated. Emotional control regulates the processing of emotional conflicts such as in irony in speech, and cognitive control resolves conflict between non-affective tendencies. While negative emotion can trigger control processes and speed ...

the experiment was designed to study the changes in production performance and egg quality of old laying hens after injection of different doses of growth hormone (gh) and testosterone (ts). a total of 160 old laying hens (hyline w-36) at 73 wks of age were randomly assigned to four treatments with four replicates and 10 birds in each replicate in a completely randomized design. treatment group...

Proton nuclear magnetic resonance (PMR) spectra at 270 MHz of aqueous dispersions of nonsonicated egg lecithin, dipalmitoyl lecithin, egg lecithin-cholesterol (1 : 1 ) and dipalmitoyl lecithin-cholesterol (1 : 1), together with PMR spectra of mitochondrial membranes and their extracted lipids, have been obtained. Carbon-13 nuclear magnetic resonance (CMR) spectra at 25.2 MHz of egg lecithin, eg...