Abstract A marine specimen of the Red Sea soft coral Dendronephthya sp. was extracted with a mixture n -hexane, diethyl ether, and methanol. One new cytotoxic steroid dendronestadione ( 1 ), five known steroids: dendronesterones A-C 2 – 4 dendrotriol 5 cholesterol 6 ) along 4-oxo-pentanoic acid 7 polyhydroxy alkane hexitol 8 were isolated from extract. The chemical structures metabolites elucid...

Hypoxia, reactive oxygen species (ROS) and oxidative stress contribute to contrast-induced acute kidney injury (CI-AKI) and ischemic reperfusion injury (IRI) in the kidney and heart. Imbalance between the increased formation of ROS by hypoxia in the cardiac and renal tissue and the low availability of endogenous antioxidants is a common cause of cellular and tissue damage. Therefore, a strategy...

Ceratonia siliqua is a legume tree of considerable commercial importance for the flavor and sweets industry cultivated mostly for its pods nutritive value and or several health benefits. Despite extensive studies on C. siliqua pod non-volatile metabolites, much less is known regarding volatiles composition which contributes to the flavor of its many food products. To gain insight into C. siliqu...

α-lipoate also known as thioctic acid, 1,2-dithiolane-3-pentanoic acid, 1,2-dithiolane-3-valeric acid or 6,8-thioctic acid has generated considerable clinical interest as a thiol-replenishing and redoxmodulating agent [16–18,27]. Lipoate has been used for a long time in Germany to treat complications associated with diabetes [11]. Recently, lipoate has also been introduced to the United States ...

The involvement of inhibitory transmitters for Ptychodiscus brevis toxin (PbTx)-induced depression of spinal synaptic transmission in neonatal rats was investigated. Stimulation of a dorsal root evoked monosynaptic reflex (MSR) and polysynaptic reflex (PSR) potentials in the segmental ventral root. The PbTx depressed the reflexes in a concentration-dependent manner and this depression was block...

OBJECTIVES/HYPOTHESIS Electronic noses can identify diseases, including head and neck squamous cell carcinoma (SCC) by the fingerprint of volatile organic compounds (VOCs) in exhaled air. However, whether these VOCs originated from the malignant lesion itself remains unclear. The objective was to test for the presence and properties of VOCs directly over the vocal folds in malignant and benign ...

Biomarkers of dietary intake are prominent tools in nutritional research. The alkylresorcinol metabolites 3,5-dihydroxybenzoic acid (3,5-DHBA) and 3-(3,5-dihydroxyphenyl)propanoic acid (3,5-DHPPA) have been proposed as exposure biomarkers of whole-grain (WG) wheat and rye intake. However, the profile of alkylresorcinol metabolites is not fully understood. The aim of this study was to investigat...

Electrochemical synthesis of poly ortho toludine (POTD) was achieved on Teflon coated cylindrical stainless steel electrodes with base diameter 2mm . Aniline in 2-propyl pentatonic acid solution was polymerized on the surface of stainless steel using cyclic voltametry technique. Adherent and red polymer films were obtained on the electrodes.. The corrosion inhibitive performance of POTD+2PPA , ...

Aims: The present research is focused on screening in vivo anti-ulcer activity using pylorus ligation and ethanol induced ulcer model. 
 Study Design: Fourty eight rats, randomly divided into groups, were used this study. Bark of Alstonia scholaris air-dried, ground fine powder the preparation an ethanolic extract.
 Place Duration Study: Department Pharmacology, Osmania University, Hy...