background: intracerebral hemorrhage (ich) is a stroke type which resulted in disability. memantine have been supposed to have the effect on the functional status in patients with ich. objectives: comparing the effect of memantine with placebo on the clinical outcome of ich. materials and methods: this double-blind clinical trial was conducted in an academic hospital in northern iran on patien...

background brucellosis is a systemic infection with a various clinical manifestations ranging from asymptomatic infection to serious and fatal diseases. in endemic area, one-third of all cases of human brucellosis have been reported in children. objectives this study aimed to evaluate epidemiology, clinical presentation, and treatment outcome of brucellosis among children in zahedan city. patie...

introduction: gynecologists and perinatologists are left with many unanswered questions and concerns regarding fasting during pregnancy and its effects on maternal and neonatal health. the current study was conducted to investigate the correlation between the number of ramadan fasting days and pregnancy outcomes. materials & methods: in this descriptive, analytical study, 641 newborns, whose mo...

introduction: to assess the efficacy and safety of bronchial artery embolization in the treatment of massive hemoptysis.   materials and methods: a retrospective study on 46 patients (26 males and 20 females) who were referred to the razavi hospital from april 2009 to may 2012 with massive hemoptysis and had bronchial artery embolization procedures. general characteristics of the patients inclu...

holoprosencephaly (hpe) is a rare congenital brain malformation associated with multiple midline facial defects. this anomaly is resulted from the failure of diverticulation and cleavage of primitive prosencephalon during weeks 4-8 of gestation. hpe is the most common forebrain developmental anomaly in human with the incidence rate of 0.49-1.2 cases per 10,000-20,000 term births. in this study,...

introduction: n-methyl-d-aspartate receptor subunits antibody (nr2-ab) is a sensitive marker of ischemic brain damage in clinical circumstances, such as cerebrovascular accidents. we aimed to assess the value of serum nr2-ab in predicting the post-cardiopulmonary resuscitation (cpr) survival. methods: in this cohort study, we examined serum nr2-ab levels 1 hour after the return of spontaneous c...

BACKGROUND Reproductive outcome studies of couples with a history of recurrent pregnancy loss (RPL) associated with a maternal or paternal carrier of a structural chromosome rearrangement are limited. Correlation of carrier status and cytogenetics of miscarriage specimens is critical to estimate subsequent pregnancy outcome. METHODS Couples found to have a structural chromosome rearrangement ...

stroke is a significant public health burden which absolutely requires more effective therapies. the approved treatment options for stroke including tissue plasminogen activators, antiplatelet agents and anticoagulants mainly bear antithrombotic effects. meanwhile, evolving investigational approaches such as collateral therapeutics and neuroprotective agents has thus far been attempted with equ...