Background. This study aimed to analyze core muscle fatigue effects on the kinematic parameters change during volleyball jump serve. Methods. The participants were sixteen experienced male volleyball players with average age, height, and body weight of 24.6 ± 1.8 years, 1.85 ± 1.6 m, and 79.5 ± 3.5 kg, respectively. This study utilized two high-resolution video cameras, a drone video, a lactat...

We recently discovered that the constitutively active Src tyrosine kinase can enhance hyperpolarization-activated, cyclic nucleotide-gated (HCN) 4 channel activity by binding to the channel protein. To investigate the mechanism of modulation by Src of HCN channels, we studied the effects of a selective inhibitor of Src tyrosine kinase, 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimi...

Let M be a manifold equipped (locally) with a pair of complementary foliations. In Catuogno, da Silva and Ruffino [4], it is shown that, up to a stopping time τ , a stochastic flow of local diffeomorphisms φt in M can be decomposed in diffeomorphisms that preserves this foliations. In this article we present techniques which allow us to extend the time of this decomposition. For this extension,...

abstract one of the most frequently encountered cases of rapid varied flow is the hydraulic jump. it occurs when a supercritical open channel flow changes into sub critical flow. in the present research, the experimental study of the hydraulic jump on seven sinusoidal corrugated beds with different wave steepness. the wave steepness of sinusoidal corrugated beds is in the range of 0.1667 to 0.7...

The E-cadherin/catenin cell adhesion system is often down-regulatedin epithelial tumors. This is thought to play an important role in cancer invasion and metastasis. Restoring this system may enable suppression of the metastatic spread of cancer. This study examined the effect of Src family kinase inhibitor PP2 on E-cadherin-mediated cell-cell adhesion and metastatic potentials. In cell aggrega...

The pathway from gene activation in the nucleus to mRNA translation and decay at specific locations in the cytoplasm is both streamlined and highly interconnected. This review discusses how pre-mRNA processing, including 5' cap addition, splicing, and polyadenylation, contributes to both the efficiency and fidelity of gene expression. The connections of pre-mRNA processing to upstream events in...

On or about 2012 August 25, the Voyager 1 spacecraft crossed the heliopause into the nearby interstellar plasma. In the nearly three years that the spacecraft has been in interstellar space, three notable particle and field disturbances have been observed, each apparently associated with a shock wave propagating outward from the Sun. Here, we present a detailed analysis of the third and most im...

Learning long-term temporal dependencies with recurrent neural networks can be a difficult problem. It has recently been shown that a class of recurrent neural networks called NARX networks perform much better than conventional recurrent neural networks for learning certain simple long-term dependency problems. The intuitive explanation for this behavior is that the output memories of a NARX ne...