The existence of long-lived reservoirs of latently infected CD4+ T cells is the major barrier to curing HIV, and has been extensively studied in this light. However, the effect of these reservoirs on the evolutionary dynamics of the virus has received little attention. Here, we present a within-host quasispecies model that incorporates a long-lived reservoir, which we then nest into an epidemio...

The clinical tools available to evaluate bone development in children are often ambiguous, and difficult to interpret. Unfortunately bone densitometry methods (i.e., dual energy X-ray absorptiometry, DXA) which have a relatively straightforward application in adult osteoporosis, are far more difficult to evaluate in the growing skeleton. Even with adequate "adjustment" for bone size or maturity...

BACKGROUND Tendon is an integral part of joint movement and stability, as it functions to transmit load from muscle to bone. It has an anisotropic, fibrous hierarchical structure that is generally loaded in the direction of its fibers/fascicles. Internal load distributions are altered when joint motion rotates an insertion site or when local damage disrupts fibers/fascicles, potentially causing...

Objective: To evaluate fracture strength of veneered translucent zirconium dioxide crowns designed with different porcelain layer thicknesses. Materials and Methods: Sixty crowns, divided into six groups of 10, were used in this study. Groups were divided according to different thicknesses of porcelain veneer on translucent zirconium dioxide cores of equal thickness (0.5 mm). Porcelain thicknes...

Solar Home System is one of the technologies for utilizing solar power at home. To optimize performance PLTS, it necessary to regulate use electrical energy. In this research, an effort made control load using fuzzy logic consumption used by so that energy can be utilized effectively. The method works based on input given desired results as expected. test effectiveness method, study was tested ...

in this paper, the mean value of strain energy density criterion has been used to predict the critical fracture load in specimens with u-shaped notch under bending loads. an equation for calculation of averaged strain energy density in this zone has been presented. bending loads under mode i have been considered. two cases have been studied: 1) the control volume only includes the semicircular ...