نتایج جستجو برای: hd
تعداد نتایج: 19518 فیلتر نتایج به سال:
Huntington disease (HD) is a degenerative disorder caused by expanded CAG repeats in exon 1 of the huntingtin gene (HTT). Patients with late-stage HD are known to have abnormal auditory processing, but the peripheral auditory functions of HD patients have yet to be thoroughly assessed. In this study, 19 HD patients (aged 40-59 years) were assessed for hearing impairment using pure-tone audiomet...
The head direction (HD) cell signal is a representation of an animal's perceived directional heading with respect to its environment. This signal appears to originate in the vestibular system, which includes the semicircular canals and otolith organs. Preliminary studies indicate the semicircular canals provide a necessary component of the HD signal, but involvement of otolithic information in ...
BACKGROUND Patients undergoing hemodialysis (HD) often develop cerebral disease complications. Furthermore, cerebral regional saturation of oxygen (rSO2) was previously reported to be significantly lower in HD patients than in healthy subjects. We aimed to identify the factors affecting the cerebral rSO2 in HD patients. METHODS Fifty-four HD patients (38 men and 16 women; mean age, 67.7 ± 1.2...
Huntington's disease (HD) is an autosomal dominant disorder caused by an expansion of glutamine repeats in ubiquitously distributed huntingtin protein. Recent studies have shown that mutant huntingtin interferes with the function of widely expressed transcription factors, suggesting that gene expression may be altered in a variety of tissues in HD, including peripheral blood. Affymetrix and Ame...
A Grey Box Neural Network Model of Basal Ganglia for Gait Signal of Patients with Huntington Disease
Introduction: Huntington disease (HD) is a progressive neurodegenerative disease which affects movement control system of the brain. HD symptoms lead to patient’s gait change and influence stride time intervals. In this study, we present a grey box mathematical model to simulate HDdisorders. This model contains main physiological findings about BG. Methods: We used artificial n...
Huntington's disease (HD) is thought to be due to genetically-programmed degeneration of neurons in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbances. It is along time since the disease started tormenting human beings, and to date, conventional medications have failed to slow down the progression of HD. ...
Objective(s) Definite diagnosis of Hirschsprung’s disease (HD) is based on histopathological study, but there are limitations associated with standard histology and histochemistry in this regard. The aim of this study was to investigate calretinin immunostaining patterns in both ganglionic and aganglionic HD intestinal specimens and to compare them with control specimens. Materials and Method...
Background: Cardiovascular mortality and morbidity are high in chronic renal failure (CRF) patients. Increased dispersion of QT intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. This study was conducted to assess the effect of hemodialysis (HD) on corrected QT (QTc) intervals and their dispersions (QTd) in chronic hemodialyzed patients. Methods: Fifty-eight p...
Torque Teno virus (TTV) is a transfusion transmitted virus that seems to be involved in several complications such as acute respiratory diseases, liver diseases, AIDS, cancer, and autoimmune reactions. In the present study the frequency of TTV was investigated among β- thalassemia (BT) and haemodialysis (HD) patients (high risk patients for TTV) in Mazandaran province, Iran. DNA was ...
روش کار: 34 بیمار با نارسایی مزمن کلیوی [21 بیمار تحت درمان با همودیالیز (HD) و 13 بیمار تحت درمان با دیالیز صفاقی [(PD) وارد مطالعه شدند و با گروه سالم شاهد (18 نفر) مورد مقایسه قرار گرفتند. از همه افراد مورد مطالعه اندازه گیری سطح سرمی مالون دی آلدئید (MDA) و ظرفیت توتال آنتی اکسیدان (TAS) بعمل آمد. اندازه گیری MDA بر مبنای تیوباربیتوریک اسید با استفاده از دستگاه فلوریمتری و توتال آنتی اکسیدا...
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