Colorectal cancer is very rare in children. Therefore, the diagnosis generally established at advanced disease. This a presentation of two cases colorectal treated Habib Bourguiba Hospital University.

colorectal cancer remains one of the major cancer- related deaths despite progress in the treatment during past decades. detection of disease at earlier stages reduces its mortality. the aim of current study was to investigate expression of cytokeratin 19 (ck19), cytokeratin 20 (ck20) and guanylyl cyclase c (gcc) mrna in peripheral blood of non- metastatic colorectal cancer patients which may r...

curcumin exhibits both cancer- preventive activity and growth inhibitory effects on several neoplastic cells including human colon cancer. serotonin and its receptors have also been implicated in tumor development. this study investigated the effect of ritanserin, a selective serotonin 5ht2a receptor antagonist, alone and in combination with curcumin on colorectal cancer cell lines. results sho...

background: in iran colorectal cancer (crc) incidence varies among various places. but we do not have any validate data that deeply explored the difference of crc in kerman province by national average. the aim of this study was to evaluate the incidence of colon cancer within a 12-year period in kerman province and to find whether the incidence of crc in kerman compared with the total incidenc...

background and aims: the aim of this study was the modeling of the incidence rates of colorectal, breast and prostate cancers using a shared component model in order to explore the spatial pattern of their shared risk factors (i.e., obesity and low physical activity) affecting on cancer incidence, and also to estimate the relative weight of these shared components. methods: in this study, the ...

background: bax and bcl-2 are the major members of bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. methods: in this study, the relative level of mrna expression of bax and bcl-2 genes was deter...

background: colorectal cancer is the third cause of cancer death in western countries. age, inadequate diet, obesity, inactivity and genetic changes are some of the risk factors of colorectal cancer. correlation of genetic diversity in homologous recombination repair system with cancer was evaluated in many recent studies. this study was done to investigate the correlation of t241m polymorphism...

  Background:The present study compared the differences between survivals of patients with colorectal cancer according to their ethnicity adjusted for other predictors of survival.   Methods: In this prospective cohort study patients were followed up from definite diagnosis of colorectal cancer to death. Totally, 2431 person-year follow-ups were undertaken for 1127 colorectal cancer patients on...