BACKGROUND Clinical practice guidelines (CPGs) aim to improve patient care, but their use remains variable. We explored attitudes that influence CPG use amongst newly qualified doctors. METHODS A self-completed, anonymous questionnaire was sent to all Foundation Doctors in England and Wales between December 2012 and May 2013. We included questions designed to measure the 11 domains of the val...

BACKGROUND Community pharmacists, pharmaceutical industry and differences in prescribing between GPs. OBJECTIVE To explore the role of the pharmacists and pharmaceutical industry representatives. METHODS A cross-sectional survey was undertaken of 1434 GPs in The Netherlands in 2001. Prescribing indicators based on general practice guidelines were used to assess the quality of prescribing. T...

BACKGROUND In Turkey, 74.1% of children between three and six years of age develop dental caries. OBJECTIVE To assess the depth of oral health and dental knowledge among paediatricians in Turkey, to determine their level of oral health education and to determine factors that were associated with higher knowledge scores. METHODS A cross-sectional survey of demographics that assessed the part...

BACKGROUND Around the world government agencies responsible for the selection and reimbursement of prescribed medicines and other health technologies are considering how best to bring community preferences into their decision making. In particular, community views about the distribution or equity of funding across the population. These official committees and agencies often have access to the b...

Structural variants are implicated in numerous diseases andmake up themajority of varying nucleotides among human genomes.Herewedescribe an integrated set of eight structural variant classes comprising both balanced andunbalanced variants, which we constructed using short-read DNA sequencing data and statistically phased onto haplotype blocks in 26 human populations. Analysing this set, we iden...

BACKGROUND Accurate diagnosis and management of hearing loss (HL) is based on valid and accurate ear-specific and frequency-specific information. This is especially relevant as non-optimal hearing amplification as part of early hearing detection and intervention programmes may result in further delays in the speech and language development of children with HL. Audiological measures utilised may...

Using the Wikipedia as a corpus, the Link-the-Wiki track, launched by INEX in 2007, aims at producing a standard procedure and metrics for the evaluation of (automated) link discovery at different element levels. In this paper, we describe the preliminary procedure for the assessment, including the topic selection, submission, pooling and evaluation. Related techniques are also presented such a...

The effect of varying donor X in otherwise structurally similar O(2)S(2)X-macrocycles (L(1): X = S, L(2): X = O and L(3): X = NH) on the corresponding assembly reactions with Cu(I) halides has been demonstrated to yield three supramolecular complexes with different architectures: L(1) resulted in a discrete dimeric complex (1), while L(2) and L(3) gave respectively 1D (2) and 2D (3) coordinatio...