We present here a molecular analysis of the region surrounding the structural gene encoding alcohol dehydrogenase (Adh) in 47 lines of Drosophila melanogaster that have each accumulated mutations for 300 generations. While these lines show a significant increase in variation of alcohol dehydrogenase enzyme activity compared to control lines, we found no restriction map variation in a 13-kb regi...

Novel water-soluble lanthanide complexes (Ln(IMI-DPA)3) have been synthesized using the task-specific ionic liquid consisting of a dipicolinic acid motif as the sensitizer of lanthanide luminescence. In Ln(IMI-DPA)3, Ln(3+) ions are in 9-fold coordination through six carboxylate oxygen atoms and three nitrogen atoms in pyridine units, and the water molecule is excluded from the coordination sph...

Mobile genetic elements can be found in almost all genomes. Possibly the most common nonautonomous mobile genetic elements in bacteria are repetitive extragenic palindromic doublets forming hairpins (REPINs) that can occur hundreds of times within a genome. The sum of all REPINs in a genome can be viewed as an evolving population because REPINs replicate and mutate. In contrast to most other bi...

Heterogeneous catalysis is commonly governed by surface active sites. Yet, areas just below the surface can also influence catalytic activity, for instance, when fragmentation products of catalytic feeds penetrate into catalysts. In particular, H absorbed below the surface is required for certain hydrogenation reactions on metals. Herein, we show that a sufficient concentration of subsurface hy...

introduction:bleeding is a common concern during functional endoscopic sinus surgery (fess) that can increase the risk of damage to adjacent vital elements by reducing the surgeon’s field of view. this study aimed to explore the efficacy of topical tranexamic acid in reducing intraoperative bleeding. materials and methods:this double-blind, randomized clinical trial was conducted in 60 patients...

background: minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. these in-vitro effects proposed minoxidil to be a potential antifibrotic agent. the present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats.  materials and methods: wis...

background cataract is one of the most common surgical procedures in the elderly. in most cases, the elderly have cardiac ischemia or chronic coronary diseases, which would lead to more ischemic events during general anesthesia. therefore, surgeons and anesthetists prefer regional aesthesia to the general one owing to its more advantages and less complications. objectives therefore, this study ...

BACKGROUND Ocular alkali burns can be associated with a poor visual outcome. The release of collagenases and proteases after the injury leads to corneoscleral melting. The role of topical steroids in such patients is controversial as they have been postulated to exacerbate corneoscleral melting. METHODS 30 patients were reviewed retrospectively after admission to King's College Hospital with ...

Abstract Progress in the creation of large-scale, artificial quantum coherent structures demands investigation their nonequilibrium dynamics when strong interactions, even between remote parts, are non-perturbative. Analysis multiparticle correlations a large system presence decoherence and external driving is especially topical. Still, scaling behavior related emergent phenomena not yet well u...