Neonatal hearing loss is the most frequent sensorial congenital defect in newborns. No data are available on worldwide prevalence of congenital deafness. World Health Organization (WHO) data indicate 1-4 cases per 1000 individuals, with a considerable increase in developing countries. A prevalence exceeding 1 per 1000 however, indicates a serious public health problem calling for urgent attenti...

Coumarin, a naturally occurring substance most frequently used as a fragrance enhancer and stabilizer, was administered in the diet of Sprague-Dawley rats at dose levels of 0, 333, 1000, 2000, 3000, and 5000 ppm or in the diet of CD-1 mice at dose levels of 0, 300, 1000, or 3000 ppm. Rats receiving 333, 1000, and 2000 ppm coumarin were exposed to these dose levels in utero and during the lactat...

Data including information on patient age, gender, who initiated the visit and call classification was collected during office hours from 12 G.P. rural teaching practices with a combined GMS patient population of 24,720, over a 2 month period. There were a total of 603 home visits, giving an annual visiting rate of 143/1000. Visiting rates varied between practices from 45 to 305/1000 per year. ...

Subjects gave magnitude estimates of the loudness of monaurally presented pure tones (1000, 1040, and 1080 Hz) and dichotically presented pairs of tones (1000 Hz to one ear plus 1040 or 1080 Hz to the other). For each monaural frequency or dichotic pair, the magnitude estimates approximated power functions of sound pressure; moreover, the monaural and dichotic loudness functions were separated ...

First, the developmental toxic potential of n-butyl acetate (BA) was examined in SpragueDawley rats following whole body inhalation exposure, 6 h day-1, from day 6 to 20 of gestation, at concentrations of 0, 500, 1000, 2000 and 3000 ppm. Maternal toxicity was evidenced by significant decreases in body weight gain at 2000 and 3000 ppm, and by reduced food consumption at 1000 ppm and higher conce...

Abstract. Climate change projections indicate that extreme snowfall is expected to increase in cold areas, i.e., at high latitudes and/or elevation, and decrease warmer mid-latitudes low elevation. However, the magnitude of these contrasting patterns their precise relations elevation scale a given mountain range remain poorly known. This study analyzes annual maxima daily based on SAFRAN reanal...

AIM Despite the well-documented burden of rheumatic heart disease (RHD) in several Pacific countries, the disease is poorly understood in New Caledonia. The aim of this study was to assess the prevalence of RHD detected by echocardiographic screening in school children. METHODS An annual RHD screening programme is conducted by the Health and Social Agency of New Caledonia for school-aged chil...