Craving is a commonly used term to describe an intense desire for a substance or behaviour; however, its underlying neurobiology is not fully characterized. We have successfully used a cue exposure paradigm with functional neuroimaging (H 2 15 O PET; PET, positron emission tomography) in abstinent opiate addicts. This study showed that salient cue exposure results in activation in the left ante...

Keloid and hypertrophic scarring represent chronic disfiguring dermatoses with a high resistance to therapy. The aim of our study was to assess for the first time the quality of life of patients with hypertrophic scars and keloids, because they suffer from quality of life impairment as much as patients with other chronic skin diseases. An item-pool was created modifying and supplementing the it...

Observational Studies: Observational studies provide a mechanism for clarifying the epidemiology and risk factors/exposures that place populations at risk for disease. Observational studies assist in identifying clinical outcomes that might aid in predicting future disease. This type of study allows researchers to draw conclusions about responses to variables; they allow for associations but no...

4. training community health extension workers and community volunteers Training CHEWs and community volunteers before MDA ensures smooth implementation. There are three phases of training. The first two-day training session is for divisional coordinators and supervisors from all over the district that will carry out MDA. The second two-day training session is for CHEWs, who are team leaders at...

BACKGROUND The need of an early and noninvasive diagnosis of AD requires the development of imagingbased techniques. As an alternative, the magnetic resonance image (MRI) relaxation time constant (T1ρ) was measured in brains of Alzheimer’s disease (AD), mild-cognitive impairment (MCI), and age-matched controls in order to determine whether T1ρ values correlated with the neurological diagnosis. ...