Gaj et al concluded that the use of anal self-massage with a finger appears to induce a better resolution of acute anal fissure than anal dilators and in a shorter time [1]. We have objections to this strategy, because anal manipulation in the traumatized area of the fissure can induce further injury and aggravate symptoms, exposing the patient to the risk of fistula or abscess formation. Anal ...

background and aims. marginal seal of the material is extremely important in fissure sealant therapy. the aim of this study was to investigate microleakage of flowable composite resins and conventional fissure sealants with or without dentin bonding agent. materials and methods. the occlusal surface of 60 intact extracted human premolars, divided into four groups, were cleaned with pumice/slurr...

A preliminary report in 1965 described a conservative surgical procedure for the management of acute and chronic horseshoe anal fistulas. The operation has been used exclusively at the Ochsner Clinic for this problem since 1963. Forty-one patients were treated from 1963 to 1973. The paper reviews the pathology of acute and chronic horseshoe anal fistulas and describes the surgical procedure for...

Background: Foot Fissure is one of the most common diseases of the foot. Objective: This study was conducted to evaluate the effect of aloe vera gel and lanolin oil on the healing process of foot fissure in the Saveh city. Methods: In this interventional study that performed on 94 patients with foot fissure in both feet, the demographic information questionnaire, dry feet clinical assessment ...

The anoctamin (ANO) family of proteins, consisting of 10 members in mammals, are transmembrane proteins that have Ca2+-activated Cl- channel activity. The transmembrane channel-like (TMC) family of proteins, consisting of 8 members in mammals, are also transmembrane proteins of which mutations are implicated in various human conditions, such as hearing loss and epidermodysplasia verruciformis. ...

background pit-and-fissure sealants are safe and effective ways to prevent dental caries and are considered as a part of an overall caries-preventive strategy. dental caries are a public health problem and the most common intraoral disease affecting mankind. it is an infectious transmissible disease, with the child patient being at the highest risk. objectives the purpose of this study was to e...

An isoenzymatic comparative analysis of the variability and genetics differentiation among Anopheles species was done in populations of An. (Nys.) intermedius and An. (Ano.) mattogrossensis of the Anopheles subgenus, and of An. darlingi, An. albitarsis and An. triannulatus of the Nyssorhynchus subgenus, with the aim of detecting differences between both subgenera and of estimating the degree of...

Coloboma is a congenital disease that contributes significantly to childhood blindness. It results from the failure in closing the optic fissure, a transient opening on the ventral side of the developing eye. Although human and mouse genetic studies have identified a number of genes associated with coloboma, the detailed cellular mechanisms underlying the optic fissure closure and coloboma form...