نتایج جستجو برای: gastric cancer
تعداد نتایج: 973988 فیلتر نتایج به سال:
abstractbackground: pathogenicity ofthe helicobacter pylori-caga positive was associated with epiyamotifs and higher number of epiya-c segments is a risk for gastric cancer,while duodenal ulcer-promoting gene (dupa) is determinedas a protective factor against gastric cancer. our aim was to determine the epiya-cagaphosphorylation sites and dupa gene in h. pylori isolates amongpatients with upper...
Absract Gastric cancer is the fourth most common cancer and the second leading cause of cancer death. Most cases are sporadic and only 10% of patients, show familial clustering. Among these patients, 1 to 3 % have hereditary diffuse gastric cancer (HDGC), which is autosomal-dominant and present in younger ages. Mutations in Ecadherin gene CDH1 has been identified in 30 to 50% of patient...
background: worldwide, cancer of stomach is still the fourth common cancer and the second cause of mortality among all cancers affecting annually 870,000 subjects. this study aims to determine the frequency and the characteristics of gastric cancer in southern iran. materials and methods: 10,800 of all cancers registered in fars hospital-based cancer registry were surveyed among which 574 cases...
Background and purpose: Mortality rate from gastric cancer is growing in the world. Nowadays, in many cancers, between cancer development and changes in EGF receptor expression levels there is a very precise relationship. Perhaps one of the best known of these changes in gastric cancer is over expression of Her1 & 2 receptors. This study investigated the expression rate of these two receptors i...
Introduction & Objective: The objective of this study was to determine the sensitivity and specificity of CA 19-9 test in diagnosis of gastric cancer patients. Materials & Methods: This prospective and cross-sectional study was carried out on 35 patients with gastric cancer and 35 patients without adenocarcinoma of gaster as a control group. Theses patients were referred to alimentary and pa...
Background: Characterization of genes and precise assessment of the number of copies are crucial for understanding the basis of emergence, progression, and identification of predictive markers of tumor malignancy. This study aimed to investigate the role of the changes in some central genes in gastric cancer. Materials and Methods: In this experimental study, 30 patients with gastric surgery w...
Background and Objective: Compelling evidence exists in favor of the effectiveness of herbal plant-derived components in cancer treatment; however their exact mechanisms of action are not well understood. Since the alteration of mitogen-activated protein kinase enzymes (MAPKs) has been reported in different cancer types, the present study aimed to investigate the effects of soy isoflavonoid gen...
Background and purpose: Recently, several studies have shown type 2 diabetes to be associated with gastric cancer and metformin appears to inhibit the growth of cancer cells by inducing apoptosis. This study was conducted to investigate the relationship between metformin and gastric cancer. Materials and methods: This case-control study included patients with gastric cancer (case group, n= 12...
Background and Aim: Like other cancers, gastric cancer is due to uncontrolled growth of tissues. Although there are different therapy methods to treat it, such as surgery, radiation therapy, chemotherapy, and multimodality therapy, relapse and death may occur. Reports show that in Iran gastric cancer is the first cause of death among deaths due to cancers. The purpose of this study was to deter...
Background and objectives: Gastric cancer is one of the most common cancers of the gastrointestinal tract in the world, which also has a high prevalence in Iran. ERCC2 gene is considered one of the major genes related to gastric cancer. The present study aimed to investigate the relationship between rs13181 polymorphism of ERCC2 gene. The polymorphism in the promoter region of ERCC2 gene can af...
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