Introduction: Dimethyl sulfoxide (DMSO) is a chemical often used as a solvent for waterinsoluble drugs. In this study, we evaluated the effect of intracerebroventricular (ICV) administration of DMSO on neural response characteristics (in 1200–1500 μm depth) of the rat barrel cortex. Methods: DMSO solution was prepared in 10% v/v concentration and injected into the later...

Introduction: Memantine as N-Methyl-D-aspartic acid (NMDA) receptor antagonist is used in some neurological disorders. It has been reported that memantine has modulatory effects on the somatosensory information processing in healthy subjects. This study investigated the effect of memantine on electrophysiological properties of barrel cortex neurons in male rats. Methods: Single unit recording ...

in acceptance-sampling plans, the items of an incoming lot are inspected one by one. if the number of nonconforming items in sample is equal zero, the lot is accepted but if the number of nonconforming items is equal to one, then second sample is taken and the policy of zero acceptance number would be applied for the second sample. in this paper, a mathematical model is developed to design sing...

Energy harvesting for the purpose of powering low power electronic sensor systems has received explosive attention in the last few years. A common device uses the piezoelectric effect for a cantilever beams at resonance to harvest ambient vibration energy. However most of these devices have a rectangular piezoelectric patch covering all or part of the beam. This paper considers the optimum desi...

Recent advances in IT have provided firms unprecedented ability to manage online social interactions. Despite growing popularity, few studies have examined firm's optimal design choices in firm-mediated social interactions. We examine whether and how a firm can enhance effectiveness of online social interactions, by simply varying message shared by referrers. We focus on two pieces of informati...

This paper investigates the role of the assumption of classconditional independence of object features in human classification learning. This assumption holds that object feature values are statistically independent of each other, given knowledge of the object’s true category. Treating features as classconditionally independent can in many situations substantially facilitate learning and catego...

This paper investigates the hypothesis that the objective function of economic agents is non-separable in economic incentives and social preferences. We study fixed-prize contests in a 2 × 2 experimental design, varying orthogonally the degree of competition of the incentive mechanism (all-pay auction vs. lottery) and the presence or absence of social returns to bidding (public good vs. rent se...

For the algorithmic construction of optimal experimental designs, it is important to be able to evaluate small modifications of given designs in terms of the optimality criteria at a low computational cost. This can be achieved by using powerful update formulas for the optimality criteria during the design construction. The derivation of such update formulas for evaluating the impact of changes...

In this work, we develop duality of the minimum volume circumscribed ellipsoid and the maximum volume inscribed ellipsoid problems. We present a unified treatment of both problems using convex semi–infinite programming. We establish the known duality relationship between the minimum volume circumscribed ellipsoid problem and the optimal experimental design problem in statistics. The duality res...