OBJECTIVE To detect the expression of the muscarinic receptor (M receptor) in different prostate tissues and analyze the role of its subtype in prostatic oncogenesis. METHODS Thirty-six cases of normal prostate and benign prostatic hyperplasia, and 8 cases of prostatic tumor, were used in this study from the Shandong University, Shandong, China, between 2003-2006. The protein expressions of M...

Using a 0.5 tesla superconducting magnetic system, magnetic resonance imaging (MRI) studies were performed in 42 patients (27 prostatic carcinoma and 15 benign prostatic hyperplasia) and 2 healthy volunteers. Spin echo images were produced in the transverse, coronal and sagittal directions. T1 and T2 relaxation times were calculated from these images. The images of 2 normal prostates showed 2 s...

Objective: To evaluate the efficacy of drug in improving lower urinary tract symptoms for improved health care and better management patients. Study Design: Randomized controlled trial Place Duration Study: Department Urology, General Medicine Surgery, Pakistan Ordinance Factories Hospital, Wah Cantt from 1st January 2021 to 31st July 2022. Methodology: One hundred patients, age more than 45 ye...

Dutasteride is a competitive inhibitor of the enzyme 5-alpha-reductase and commonly used to treat symptoms benign prostatic hyperplasia (BPH).
 Objective: determine efficacy safety dutasteride in terms indicators that are important clinical practice.
 Data sources. The literature was searched using search «prostate hyperplasia», hypertrophy», «dutasteride», «quality life», «adverse dr...

Background Information: Currently alpha1-adrenoreceptor blockers with the combination of 5- alpha reductase inhibitors are widely used as first-line therapy to improve Lower urinary tract symptoms (LUTS) associated Benign Prostatic Hyperplasia (BPH). Aims And Objectives:The aim this study was evaluate Efficacy drug Silodosin and Dutasteride in patients mild severe symptoms. Materials Methods:Th...

Background and Objective: Benign Prostatic Hyperplasia (BPH) is defined as the enlargement of prostate gland in presence urinary symptoms without any evidence malignancy. For patients who have failed medical treatment first line therapy, surgical intervention will be administered treatment. Hemorrhage one most dreadful serious complications surgery. Bleeding can often significant lead to increa...

PURPOSE Previous studies suggest that vascular endothelial growth factor (VEGF) circulating levels might improve identification of patients with prostate cancer but results are conflicting. Our aim was to compare serum VEGF levels across different prostate pathologies (including benign prostatic hyperplasia, prostatitis, high grade prostate intraepithelial neoplasia and prostate cancer) in pati...