نتایج جستجو برای: and treatment 2

تعداد نتایج: 17445409  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Timothy Kottke Jill Thompson Rosa Maria Diaz Jose Pulido Candice Willmon Matt Coffey Peter Selby Alan Melcher Kevin Harrington Richard G Vile

PURPOSE The goals of this study were (a) to investigate whether preconditioning of immunocompetent mice with PC-61-mediated regulatory T-cell (Treg) depletion and interleukin-2 (IL-2) would enhance systemic delivery of reovirus into subcutaneous tumors and (b) to test whether cyclophosphamide (CPA), which is clinically approved, could mimic PC-61 for modification of Treg activity for translatio...

پایان نامه :دانشگاه امام رضا علیه اسلام - دانشکده ادبیات و زبانهای خارجی 1393

abstract this mixed method study examines whether there is any relationship among the variables of the study (job satisfaction, social capital and motivation). the researcher considered job satisfaction and social capital as independent variables; motivation is the dependent variable of the study. the researcher applied a questionnaire to assess each variable. to measure efl teachers’ job sati...

The potential function of Lippincott and Schroeder for linear hydrogen bond has been re-examined and extended to nonlinear hydrogen bond. The parameters originally introduced to the potential function by Lippincott and Schroeder have been determined from the structural parameters such as 0.. .Odistance 0-H bond distance, H.. .O distance and HOO angle. Thevalidity of harmonic oscillator appr...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده دامپزشکی 1389

چکیده: بررسی مقایسه ای گونه های مختلف مالاسزیا در پوست و گوش گوساله های نوزاد با مادرانشان با استفاده از روشهای مورفولوژیکی، بیوشیمیایی و فیزیولوژیکی مخمرهای لیپوفیلیک جنس مالاسزیا جزء فلور نرمال جلدی انسان و حیوانات می باشند که تحت شرایطی بیماریزا می شوند. از آنجایی که نه تنها گونه غیر وابسته به چربی بلکه سایر گونه های مالاسزیا از حیوانات مختلف جداسازی می شود لذا بررسی اپیدمیولوژی و انتشار ج...

Cyclooxygenase-2 (COX-2) has a pivotal role in the pathogenesis of the lung cancer. It is known that COX-2 negatively regulates the activity of a number of tumor suppressors, including p53. Consequently, inhibition of COX-2 signaling is anticipated to be a promising approach to stabilize p53 functionality. In this regard, we investigated the effect of COX-2 signaling blockade on p53 and COX-2 e...

ژورنال: یافته 2021
Badrizadeh, Afsaneh, Foroughi, Saeid, Khanzadeh, Mostafa, Rezaii Jamaloi, Hasan, Saki, Mandana,

Background: According to the growing prevalence of type 2 diabetes, the present study aimed to predict adherence to treatment based on social support variables and coping strategies to reduce the severity of this disease. Materials and methods: In this cross-sectional study, 392 men and women with type 2 diabetes were evaluated using purposeful and convenient sampling. Wax social support and t...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده علوم 1375

this thesis basically deals with the well-known notion of the bear-invariant of groups, which is the generalization of the schur multiplier of groups. in chapter two, section 2.1, we present an explicit formula for the bear-invariant of a direct product of cyclic groups with respect to nc, c>1. also in section 2.2, we caculate the baer-invatiant of a nilpotent product of cyclic groups wuth resp...

Journal: :Nihon Naika Gakkai Zasshi 1975

Background and purpose: Ascorbic acid is an important antioxidant and its depletion is a risk factor for periodontal diseases. This study aimed to evaluate the effect of 2% atorvastatin dentifrice and ascorbic acid on improving clinical periodontal parameters in patients with chronic periodontitis. Materials and methods: This clinical trial included 72 patients with moderate and severe chronic...

Journal: :Chemical communications 2015
Yang Xu Ling Xu Yuan Xia Chao-Jian Guan Qing-Xiang Guo Yao Fu Chen Wang Yi-Ming Li

Rapid and catalyst-free hydrazone ligation reaction between ortho-halobenzaldehyde derivatives and peptide/protein hydrazides was observed at neutral pH and room temperature. 2-Chlorobenzaldehyde exhibited the fastest reaction and highest conversion rates among the series of ortho-halobenzaldehydes. The resulting hydrazone-containing bioconjugation products were also found to be fairly stable u...

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