background and aims: crocus sativus is of medicinal plants possessing many beneficial effects in treatment of various disorders. this study aimed to overview the therapeutic effects of crocus sativus on the basis of reviews and systematic reviews. methods: computerized search of review articles was performed using pubmed, google scholar, scopus and web of science, medline database from 1996 to ...

Saffron petal is the main by-product of saffron processing which produced at high level but it is not applied and thrown out. Saffron petal is containing of several compounds such as mineral agents, anthocyanins, flavonoids, glycosides, alkaloids and kaempferol. As saffron petal is cheaper and produces in large amounts compared to saffron stigma, so, it can be considered as an appropriate sourc...

The phenomenon of dextromethorphan (dextro) abuse is rife in Indonesia. Several cases indicate the occurrence this abuse. As an example case dextro that occurred Manado, North Sulawesi, a woman with initials IR (25), was found dead hotel room Wanea sub-district, Saturday (09/05/2020) after consuming liquid cough medicine containing dextro. Dextro dextro) On (5/9/2020), (25) District, Sulawesi. ...

Notwithstanding their key roles in therapy and as biological probes, 7% of approved drugs are purported to have no known primary target, and up to 18% lack a well-defined mechanism of action. Using a chemoinformatics approach, we sought to "de-orphanize" drugs that lack primary targets. Surprisingly, targets could be easily predicted for many: Whereas these targets were not known to us nor to t...

This article is devoted to one of the most common manifestations of diseases of respiratory system and upper respiratory tract coughing. While performing a protective function , the cough in some cases significantly impairs a child's condition. The choice of treatment requires a clear understanding of the mechanism of a drug's action, its safety profile and effectiveness. In this paper the auth...

picralima nitida is used traditionally for management of cough. this study, therefore, investigated the antitussive, expectorant, and analgesic properties of the ethanolic seed extract of picralima nitida (pne), and ascertained its safety for use. presence of secondary metabolites, and safety of pne (10-2000 mg/kg) were evaluated by preliminary phytochemical screening, and by irwin’s test respe...

Rosa damascena mill L., known as Gole Mohammadi in Iran is one of the most important species of Rosaceae family flowers. R. damascena is an ornamental plant and beside perfuming effect, several pharmacological properties including anti-HIV, antibacterial, antioxidant, antitussive, hypnotic, antidiabetic, and relaxant effect on tracheal chains have been reported for this plant. This article is a...