Contour Crafting is an emerging technology that uses robotics to construct free form building structures by repeatedly laying down layers of material such as concrete. The Contour Crafting technology scales up automated additive fabrication from building small industrial parts to constructing buildings. Tool path planning and optimization for Contour Crafting benefit the technology by increasin...

Performance prediction of checkpointing systems in the presence of failures is a well-studied research area. This paper makes three small contributions to this research area. First, we show how to apply the concept of availability from reliability theory as a useful metric for checkpointing systems. Second, we study the average availability of uniprocessor checkpointing systems, using the libck...

The main goal of this article is to implement the MSG-3 process in structure field for an SSI component of b747 aircraft. This process is expected toincrease the ease of aircraft maintenance and its safety level. MSG-3 logic took a top-down or consequence of failure approachmeaning that MSG-3 reduces the maintenance cost and upgrades safety. Moreover, it cansignificantly help saving thetime and...

In their editorial, Speed and Mannion identify two main challenges “the rise of post-truth populism” poses for health policy: the populist threat to inclusive healthcare policies, and the populist threat to well-designed health policies that draw on professional expertise and research evidence. This short comment suggests some conceptual clarifications that might help in thinking through more p...

The most straightforward way to reduce network power consumption is to turn off idle links and nodes (switches/routers), which we call the power down approach. In a wired network, especially in a backbone network, many links are actually “bundles” of multiple physical cables and line cards that can be shut down independently. In this paper, we study the following routing problem for green netwo...

Avian forelimb digit homology remains one of the standard themes in comparative biology and EvoDevo research. In order to resolve the apparent contradictions between embryological and paleontological evidence a variety of hypotheses have been presented in recent years. The proposals range from excluding birds from the dinosaur clade, to assignments of homology by different criteria, or even ass...

Although infants with persistent pulmonary hypertension of the newborn (PPHN) experience some relief and therapeutic benefit from current therapies, over 50% have a limited or transient response and significant morbidity. There is no consistency in the best first line treatment throughout hospitals in the United States. Ventilation with high levels of oxygen or inhaled nitric oxide (NO) are typ...

In this issue, Limpitikul et al used the novel CRISPR interference (CRSPRi) strategy to suppress the expression of an arrhythmogenic mutant calmodulin (CaM) gene in human induced pluripotent cell-derived cardiomyocytes (iPSC-CM). This mutant CaM (D130G) is linked with long-QT syndrome (LQTS). The main LQTS mechanism is via a loss in Ca affinity of CaM, resulting in a loss of Ca-dependent inacti...

The aim of this course is to provide the student with a deep understanding of the principles, structure, and operation of computer networks. The student completing this course should have a strong knowledge of the protocols and mechanisms used in the Internet, and of the design and operation of both wide-area and local-area computer/communication networks. The course will also involve implement...