BACKGROUND Cytoplasmic inclusion bodies within hepatocytes may have different etiologies, including the Endoplasmic Reticulum Storage Diseases (ERSDs). ERSD is a pathological condition characterized by abnormal accumulation of proteins destined for secretion in the endoplasmic reticulum of hepatocytes; it may be congenital (primary) or acquired (secondary). Fibrinogen storage disease is a form ...

ariri eiles ?f 46 cases with 86 per cent mortality, pother of 45 cases with 100 per cent criu^^y. Loutsch and Merigot (1934) des10 cases with a mortality of 40 per cent. Lipshutz and Lowenburg (1926) report 23 cases of pneumococcal peritonitis and streptococcal peritonitis in children under 6 years of age, each with a mortality of 100 per cent. Newell (loc. tit.) states that in the literature t...

Retroperitoneal fibrosis (RPF) is a chronic retroperitoneal inflammatory process that can entrap the retroperitoneal structures, mainly the ureters and the great vessels. Aetiology, clinical features and diagnostic appearance in several cases are protean. A true idiopathic form is present in any cases of RPF in which no potential aetiologic condition may be identified. The pathogenesis of the i...

Rosen et al. first described pulmonary alveolar proteinosis (PAP) in 1958. PAP is characterized by the accumulation of phospholipoproteinaceous material in alveolar spaces. The prevalence of PAP is difficult to determine from the literature, however, it is rare. The etiology of this disorder is not yet known. There are two types of PAP based on associated disorders: primary (idiopathic) type, i...

Idiopathic pulmonary haemosiderosis is a rare disorder, with recurrent life-threatening alveolar haemorrhages and chronic lung parenchymal changes. It associated triad of haemoptysis, iron deficiency anaemia, diffuse infiltrates. Although most cases are idiopathic, secondary linked to known diseases has also been observed. Most the remain undiagnosed because disease very low on list differentia...

tuberculosis (tb) still represents a major public health problem worldwide. the primary form of disease is most often localized to the lung. in a minority of patients, progressive pulmonary disease spreads to other organ systems through self inoculation via infected sputum, blood and lymphatic system, establishing the secondary form of tuberculosis . we present a patient that was referred to us...