seeds of moringa peregrina (forssk.) fiori. (moringaceae) is widely used in south east of iran for gastrointestinal disorders. however, so far there is no pharmacological evidence for antispasmodic activity of this plant extract. therefore, the aim of this research was to investigate antispasmodic activity of m. peregrina on rat isolated ileum contraction. hydroalcoholic extract was obtained by...

Previous studies have demonstrated that magnesium and zinc ions promote the migration and epithelial-mesenchymal transition (EMT) of cancer/endothelial cells. However, the impact of MgCl2 and ZnCl2 on the migration, invasion and EMT of human umbilical vein endothelial cells (HUVECs) and the involved mechanisms remain unclear. In the present study, HUVECs were incubated with various doses of MgC...

it has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. the exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and cardiovascular disorders. to determine the probable effect of aluminium on vasculature function, in vitro effects of aluminium ion on vasocons...

Inclusions in mantle minerals and xenoliths from kimberlites worldwide derived depths exceeding 100 km vary composition alkali-rich saline to carbonatitic. Despite the wide distribution of these melts their geochemical importance as metasomatic agents that altered mineralogy geochemistry rocks, P-T range stability remains largely undefined. Here we report new experimental data on phase relation...

Both Mg2+ and Ca2+ have been implicated as having roles in the pathomechanisms of cerebral ischemia. To further study the effects of these ions on postischemic histologic outcome, fasted rats were given one of three intravenous infusions: 5.0 mmol/kg MgCl2, 5.0 mmol/kg MgCl2 + 0.035 units/kg regular insulin, or 1.0 mmol/kg CaCl2. This resulted in elevated plasma Mg2+ or Ca2+ concentrations in t...

We have investigated the interaction of divalent ions with chromatin towards a closer understanding of the role of metal ions in the cell nucleus. The first row transition metal ion chlorides MnCl2, CoCl2, NiCl2 and CuCl2 lead to precipitation of chicken erythrocyte chromatin at a significantly lower concentration than the alkali earth metal chlorides MgCl2, CaCl2 and BaCl2. A similar distincti...

Heterogeneous Ziegler-Natta and homogeneous metallocene catalysts exhibit greatly different active sitenature in olefin polymerization. In our previous study, it was reported that MgCl2-supported titanocenecatalysts can generate both Ziegler-Natta-type and metallocene-type active sites according to the type of activators.The dual active site nature of the supported titanocene catalysts was furt...