The term "INDUSTRY 4.0" or "fourth industrial revolution" was first introduced at the fair in 2011 in Hannover. It comes from the high-tech strategy of the German Federal Government that promotes automation-computerization to complete smart automation, meaning the introduction of a method of self-automation, self-configuration, self-diagnosing and fixing the problem, knowledge and intelligent d...

background l-tryptophan is an important ingredient in medicines, especially in neuromedicines such as antidepressants. many commercial processes employ various microorganisms with high tryptophan synthase activity to produce l-tryptophan from indole and l-serine, but these processes are very costly due to the costs of precursors, especially l-serine. objectives for this reason, we studied the a...

crude glycerol (cg) is an abundantly available and cheap by-product from biodiesel production. value-added applications for cg are highly wanted by industry and several processes such as the use of cg for enhanced oil recovery have been proposed. the aim of this study was to evaluate the sulfide production of sulfate-reducing bacteria (srb) indigenous to oil reservoirs using cg as substrate. th...

background: enzymatic hydrolysis of lactose is one of the most important biotechnological processes in the food industry, which is accomplished by enzyme β-galactosidase (β-gal, β-d-galactoside galactohydrolase, ec 3.2.1.23), trivial called lactase. orthogonal arrays design is an appropriate option for the optimization of biotechnological processes for the production of microbial enzymes. metho...

Performance measurement in the presence of fixed-sum outputs in data envelopment analysis (DEA) is an interesting and most frequently studied subject in the field of operations research. Different definitions of relative efficiency in the presence of fixed-sum outputs have been proposed in the literature of data envelopment analysis and in all of the existing definitions a common equilibrium ef...

traceability is an ability of system to provide status reports or records pertaining of the current situation in the past. in production systems, traceability to track the product or lot of a product and access to records in the entire production process (or part of the process) of the raw material to finished product that purchased and consumed by customer will be applied. traceability in prod...

the method of entropy production minimization for finding energy efficient paths of operation of process equipment is first presented using an instructive example with optimal control theory. with refer-ence to the earlier investigations, the researchers present some design rules that relate to the designs’ en-tropy production. minimum entropy production is not obtained in special cases, not ge...