In C. elegans, genome-wide screens have identified just five essential centriole-duplication factors: SPD-2, ZYG-1, SAS-5, SAS-6, and SAS-4 [1-8]. These proteins are widely believed to comprise a conserved core duplication module [3, 9-14]. In worm embryos, SPD-2 is the most upstream component of this module, and it is also essential for pericentriolar material (PCM) recruitment to the centriol...

Paracoccidioidomycosis (PCM) is a granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis. The immunoglobulin classes and isotypes of antibodies directed to acidic glycosphingolipids (GSLs) and glucosylceramide of P. brasiliensis were determined by enzyme-linked immunosorbent assay of sera from 31 PCM patients. The reactivities of 38 serum samples were analyzed by con...

many researchers have investigated how to increase the overall efficiency of solar-driven thermal systems. several key parameters, such as collector efficiency and storage tank characteristics, may impose some constraints on the annual solar fraction (asf) of such systems. in this paper, the behaviour of integrating the phase change material (pcm) in sdhw systems is modelled and optimized numer...

Centrosome asymmetry has been implicated in stem cell fate maintenance in both flies and vertebrates [1, 2]. Drosophila neuroblasts, the neural precursors of the fly's central nervous system [3], contain molecularly and physically asymmetric centrosomes, established through differences in pericentriolar matrix (PCM) retention [4-7]. For instance, the daughter centriole maintains PCM and thus mi...

Codecs used in telephone networks in the United States have a -law companding characteristic solely designed for the purpose of transmitting voice signals [1, 2]. These -law codecs are not well suited for the latest generation of high-speed digital voiceband modems requiring PCM data transmission at the quantization levels of the codec [3, 4, 5, 6, 7, 8, 9]. In this paper, we have shown that us...