Preliminary phytochemical screening of petroleum ether and alcohol extract of Symplocos Racemosa Roxb was carried out which indicates that alcoholic extract contain carbohydrate, glycoside, saponin and terpenoid & alkaloid and ether extract indicated presence of glycoside, phytosterol and steroid. An antibacterial evaluation of the petroleum ether and ethanolic extract was carried out and it is...

Background and objectives: Bacterial antibiotic resistance is a major issue in the process of infectious disease treatments. The aim of this study was an evaluation of the antibacterial activity of Punica granatum flower extract against several gram-negative and positive clinical bacterial isolates.   Methods: An adequate dried flower of an endemic mature Punica granatum plant was used for ex...

Selective antihistamine receptor type 2 blockers are widely used for treatment of peptic ulcer, these drugs are famotidine,cimetidine,nizatidine and ranitidine and because many nonantibiot ics agents have antibacterial activity so this study aimed to evaluate the antibacterial effects of selective H2 blockers. Tewnty two of bacterial strains were slected 5 Staphylococcus aureus,5 Escherichia co...

Background and objectives: Dorema ammoniacum D. Don (Apiaceae) is a monocarpic plant endemic to central Iran. The gum resin of this species is a known therapeutic agent in Iranian, Indian and Western traditional medicines. The aim of the present study was to investigate essential oil constituents and evaluation of antioxidant and antibacterial activities of the essential oils and extracts of D....

EVALUATION OF ANTIFUNGAL, ANTIBACTERIAL AND CYTOTOXIC EFFECTS SOME NEW DERIVATIVES SPIROOXYINDOLES

Twenty of the known and newly synthesized derivatives of pyrido-1,2-thiazine derivatives 3-7, which represent a novel class of potential antibacterial agents, were evaluated against strains of Mycobacterium fortuitum (PCM 672) and Staphylococcus aureus (PCM 2602). The pilot experiments showed that the compounds in an initial in vitro microbiological evaluation were not efficient antibacterial a...