since the incidence of symptomatic congenital cytomegalovirus infection is low (~0.05%) and risk factors are not well defined, it is difficult to develop strategies for prevention. the aim of this study was to recognise the utility of specific immunoglobulin g avidity analysis for distinguishing primary infection from past/recurrent infection. sera from 50 women with cytomegalovirus specific im...

The controlled digestion of human immunoglobulin M (IgM) (Patient Dau.) with papain in the presence of 0.002 M mercaptoethylamine resulted in the release of a basic subunit-like fragment which we designated IgM,. It resembled the subunit (IgM,) produced by mild reduction of IgM in the following ways. The molecular weight (186,000) and sedimentation coefficient (6.2 to 6.5 S) of IgM, were simila...

Background: Rheumatoid arthritis (RA) is characterized by autoantibodies such as rheumatoid factor (RF) and anti-modified protein (AMPAs) like anti-citrullinated antibodies (ACPA) anti-carbamylated (anti-CarP). Recently, another AMPA: anti-acetylated (AAPA) have been found in RA patients [1]. The prevalence of AAPA their isotypes yet to be determined. Since isotype profiles reflect the breadth ...

IgM nephropathy (IgMN) is an idiopathic immune complex-mediated glomerulopathy that was first described as a distinct disease in a nephropathology literature in 1978. Here, a historical review and the current status of IgMN in the light of world literature and the current experience will be presented. The Pubmed (www.pubmed.gov) search was made for articles on IgMN as the sole subject of the st...

Results: The findings revealed that among papilloma cases, 30 (85.7%) exhibited normal levels of both IgM and IgG, while 5 cases (14.3%) showed normal IgM levels and elevated IgG levels. Additionally, 10 cases (66.7%) of papilloma demonstrated increased IgM levels and normal IgG levels, in contrast to 5 cases (33.3%) with elevated levels of both IgM and IgG. Importantly, a positive correlation ...