نتایج جستجو برای: receptor effects

تعداد نتایج: 2029798  

Synthetic cannabinoids (SC) are a heterogeneous group of substances with a high affinity for cannabinoid receptors. Unlike Δ9-tetrahydrocannabinol (THC), synthetic cannabinoids are incredibly potent, highly productive, have more affinity for the Cannabinoid receptor type 1 (CB1), and Cannabinoid receptor type 2 (CB2), and are designed to accelerate the effects of tetrahydrocannabinol. Also, the...

Journal: :iranian biomedical journal 0
محمدرضا صفری mohammad-reza safari حشمت ا... طاهرخانی heshmatollah taherkhani محسن آنی mohsen ani غلام علی نادری gholam-ali naderi صدیقه اصغری sedige asgary

the affinity of low density lipoprotein (ldl) to its receptor is very important, because most of ldl-uptake pathway is done by the ldl receptor and the change in size of ldl particle and the modification in its components may affects the ldl affinity for its receptor. in this study, the effects of lipophilic agents such as vitamin e and seven volatile oils: anethol, eugenol, geraniol, limonene,...

Introduction: Cardiac preconditioning is an important method to reduce the damage caused by prolonged ischemia. Previous studies have shown that corticosteroids have protective effects on the heart, however at high concentrations this effect may be reduced with unknown mechanisms. We hypothesize that the contradictory effects of hydrocortisone at high concentration may be mediated via minera...

Gholam-Ali Naderi, Heshmatollah Taherkhani, Mohammad-Reza Safari, Mohsen Ani, Sedige Asgary,

The affinity of low density lipoprotein (LDL) to its receptor is very important, because most of LDL-uptake pathway is done by the LDL receptor and the change in size of LDL particle and the modification in its components may affects the LDL affinity for its receptor. In this study, the effects of lipophilic agents such as vitamin E and seven volatile oils: anethol, eugenol, geraniol, limonene,...

Journal: :مجله دانشگاه علوم پزشکی قم 0
شادی سرهرودی sh sarahroodi ahwaz jondishapour university of medical sciencesدانشگاه علوم پزشکی جندی شاپور اهواز اردشیر ارضی a arzi ahwaz jondishapour university of medical sciencesدانشگاه علوم پزشکی جندی شاپور اهواز محمدرضا زرین دست mr zarrindast tehran university of medical sciencesدانشگاه علوم پزشکی تهران محمد جواد خدایار mj khodayar ahwaz jondishapour university of medical sciencesدانشگاه علوم پزشکی جندی شاپور اهواز

background and objectives cannabinoids which are active compounds of marijuana show some pharmacological effects similar to the opioids. there are also functional interactions between both cannabinoid and opioid systems. in this study we investigated the role of cannabinoid receptors in central amygdala and its interaction with opioid system.   methods in the present study, we investigated the ...

Abolghasemi, Masoumeh Sabetkasai, Mohammad Reza Zarrindast,

In the present study, the effects of different doses of nicotine on immobility time in mice were tested. Intraperitioneal administration of low doses of nicotine (0.025 mg/kg) decreased, but higher doses (0.8 and 1 mg/kg) increased immobility time. The anti-immobility response induced by low doses of nicotine was inhibited by high doses of the D2 receptor antagonist sulpiride, the central nicot...

اصغری , لادن, فرزین , داوود,

Background and purpose: Histamine is a neurotransmitter present in the brain of mammals which produces its physiological effects on target cells by stimulation of three types of receptors H1, H2 and H3. Various reports nowadays indicate the role of histamine in reduction of pain transmission. This study was designed to determine the role of histamine receptors in reduction of pain. Mate...

B MOUSTAFAVI-MEHR , M GHAZI-KHANSARI, M REZAYAT, MR ZARRINDAST,

The effects of cholecystokinin (CCK) receptor antagonists on hypothermia induced by cocaine or morphine have been studied in mice. In the present work, subcutaneous (SC) injection of cocaine (50-150 mg/kg) or morphine (125-500 mg/kg) induced hypothermia in mice. Administration of CCKA receptor antagonist MK-329 (0.5-1.5 mg/kg), CCKB receptor antagonist L-365, 260 (0.5-1.5 mgl kg) and CCK r...

M REZAYAT, MR ZARRINDAST, MR ZOLFAGHARPOOR,

In the present study the effects of both CCK receptor agonists and antagonists on antinociception induced by morphine in the tail-flick test have been evaluated. M orphine induced dose-dependent antinociception in mice. The response of morphine was potentiated by sulfated cholecystokinin-8 (CCK-8S) but not by unsulfated cholecystokinin-8 (CCK-8U). The CCK receptor antagonists MK-329 and L-...

2012
Kathrin Müller

We investigate the competitive effects of the merger between Delta Air Lines and Northwest Airlines (2009) in the domestic U.S. airline industry. Applying fixed effects regression models we find that the transaction led to short term price increases of about 11 percent on overlapping routes and about 10 percent on routes which experienced a merger-induced switch of the operating carrier. Over a...

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